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Merck
모든 사진(1)

주요 문서

413A-1

Sigma-Aldrich

GLUT3 Rabbit Polyclonal Antibody

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41
클론:
polyclonal
application:
IHC (p)
종 반응성:
human
기술:
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
citations:
2

생물학적 소스

rabbit

Quality Level

100
500

결합

unconjugated

항체 형태

Ig fraction of antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

양식

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (413A-14)
vial of 0.5 mL concentrate (413A-15)
bottle of 1.0 mL predilute (413A-17)
vial of 1.0 mL concentrate (413A-16)
bottle of 7.0 mL predilute (413A-18)

제조업체/상표

Cell Marque

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

제어

embryonal carcinoma, yolk sac tumor

배송 상태

wet ice

저장 온도

2-8°C

시각화

membranous

유전자 정보

human ... SLC2A3(6515)

일반 설명

Glucose transporter membrane 3 (GLUT3) is known as a solute carrier family 2 (facilitated glucose transporter) member 3 and represents a membrane bound glucose transporter. In one study scientists, using immunoprecipitation and western blot technologies, detected GLUT3 expression in spermatozoa of testis and brain but not in other types of tissue. In-house research via immunohistochemistry confirmed GLUT3 expression in testis/spermatozoa, but no GLUT3 was detected in brain. In a study conducted by Howitt BE et. al. anti-GLUT3 demonstrated membranous staining of seminoma cells in 44 cases (65%) of total 67 specimens. In addition, anti-GLUT3 labeled embryonal carcinoma (20/20) and yolk sac tumor (8/8) with 100% sensitivity.GLUT3 is not expressed in non-germ cell tumors such as leydig cell tumor and adenomatoid tumor.Spermatocytic seminoma, choriocarcinoma, and immature teratoma are also negative for GLUT3. Therefore, anti-GLUT3 is a very useful IHC marker to include in a panel for identification of germ cell tumors.

품질


IVD

IVD

IVD

RUO

결합

GLUT3 Positive Control Slides, Product No. 413S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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시험 성적서(COA)

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문서 라이브러리 방문

Brooke E Howitt et al.
Applied immunohistochemistry & molecular morphology : AIMM, 21(5), 401-407 (2013-01-25)
Testicular germ cell tumors (TGCT) are the most common type of testicular tumor and encompass different histologic types that greatly influence treatment and prognosis. Immunohistochemical studies may be required for accurate classification, particularly when these tumors present at extragonadal sites
R S Haber et al.
Endocrinology, 132(6), 2538-2543 (1993-06-01)
The tissue distribution of the GLUT3 glucose transporter protein was examined in human tissues using a rabbit antiserum directed against the C-terminal peptide sequence of human GLUT3. This anti-serum was shown to recognize the human GLUT3 protein in Chinese hamster

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