추천 제품
생물학적 소스
rabbit
Quality Level
100
500
결합
unconjugated
항체 형태
Ig fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
설명
For In Vitro Diagnostic Use in Select Regions (See Chart)
양식
buffered aqueous solution
종 반응성
human
포장
vial of 0.1 mL concentrate (403A-74)
vial of 0.5 mL concentrate (403A-75)
bottle of 1.0 mL predilute (403A-77)
vial of 1.0 mL concentrate (403A-76)
bottle of 7.0 mL predilute (403A-78)
제조업체/상표
Cell Marque™
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
배송 상태
wet ice
저장 온도
2-8°C
시각화
cytoplasmic, membranous
유전자 정보
human ... CR2(1380)
일반 설명
Complement component C3 is an integral part of the classical, lectin, and alternative complement pathways, and its cleavage products are involved in immune responses such as opsonization and cell lysis. C3d is a fragment of C3 that normally binds to pathogen surfaces to promote B-cell activation. However, deposition of C3d has also been observed in peritubular capillaries of transplanted kidneys undergoing acute allograft rejection.
품질
 IVD |  IVD |  IVD |  RUO |
결합
C3d Positive Control Slides, Product No. 403S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
물리적 형태
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
제조 메모
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
기타 정보
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
법적 정보
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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시험 성적서(COA)
Lot/Batch Number
Katrin Pfaltz et al.
Journal of cutaneous pathology, 37(6), 654-658 (2009-10-30)
Direct immunofluorescence (DIF) testing is an important procedure in the diagnosis of autoimmune bullous dermatoses. We investigated the expression of C3d in formalin-fixed, paraffin-embedded tissue of autoimmune bullous dermatoses. The immunohistochemical expression of C3d in bullous pemphigoid (BP) (n =
G Eggertsen et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 109(12), 825-834 (2002-02-16)
Among patients with early severe impairment of renal allograft function we have previously identified a group displaying isolated deposition of complement factor C3 in glomeruli. Here we studied the pattern of complement deposition more extensively in allograft biopsies from five
Alice Bickerstaff et al.
The American journal of pathology, 173(2), 347-357 (2008-06-28)
Acute humoral rejection (AHR), which occurs in up to 8% of kidney transplant recipients, is a significant cause of renal allograft dysfunction and loss. More efficacious treatment modalities are needed to eliminate or curtail alloantibody production and its deleterious effects
Dirk R J Kuypers et al.
Transplantation, 76(1), 102-108 (2003-07-17)
C4d deposition in peritubular capillaries (PTCs) is a sign of humoral renal allograft rejection and an independent predictor of graft survival. Few investigators have focused on the meaning of capillary C3 deposition in rejecting grafts. Because C3 production can result
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