387R-1

Olig2 (EP112) Rabbit Monoclonal Primary Antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: EP112, monoclonal
• 설명: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• 양식: buffered aqueous solution
• 종 반응성: human
• 포장: bottle of 1.0 mL predilute (387R-17); bottle of 7.0 mL predilute (387R-18); vial of 0.1 mL concentrate (387R-14); vial of 0.5 mL concentrate (387R-15); vial of 1.0 mL concentrate (387R-16)
• 제조업체/상표: Cell Marque^®
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• 동형: IgG
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 유전자 정보: human ... OLIG2(10215)

설명

일반 설명

Olig2, a basic helix–loop–helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas.^1-2 More than half of glioblastomas are weakly positive for Olig2. No Olig2 expression has been found in the non-glial tumors including neuroepithelial tumors, ependymomas, subependymomas, medulloblastomas, and nonneuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and haemangioblastomas.^1-2 In order to characterize cellular subtypes that constitute astrocytomas, oligoastrocytomas and oligodendrogliomas, double labeling of Olig2 and GFAP has been performed which identified two phenotypically distinct tumor populations. The first is Olig2+/GFAP– which has an oligodendroglial morphology, corresponding to pure oligodendrogliomas that contain only oligodendroglial cells; the second is Olig2–/GFAP+ which has an astrocytic phenotype, including not only oligoastrocytomas, but also WHO astrocytomas.^1-2

품질

IVD

IVD

IVD

RUO

결합

Olig2 Positive Control Slides, Product No. 387S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany