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Merck
모든 사진(1)

주요 문서

244R-1

Sigma-Aldrich

DOG1 (SP31) Rabbit Monoclonal Antibody

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모든 사진(1)

About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

SP31, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

양식

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (244R-14)
vial of 0.5 mL concentrate (244R-15)
bottle of 1.0 mL predilute (244R-17)
vial of 1.0 mL concentrate (244R-16)
bottle of 7.0 mL predilute (244R-18)

제조업체/상표

Cell Marque®

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

동형

IgG

제어

GIST

배송 상태

wet ice

저장 온도

2-8°C

시각화

cytoplasmic, membranous

유전자 정보

human ... ANO1(55107)

일반 설명

DOG1 is a calcium-dependent chloride channel protein that is encoded by a gene called TMEM16A (TMEM16 FLJ10261, ANO1, ORAOV2, and AOS2) located on chromosome 11q13. DOG1 has many significant functions such as regulation of the cholinergic activity of gastrointestinal smooth muscle and regulation of both the survival and proliferation of cells. Anti-DOG1 antibody has been shown to be useful in the identification of gastrointestinal stromal tumors (GIST).

품질


IVD
IVD
IVD
RUO

결합

DOG1 Positive Control Slides, Product No. 244S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
0000320459
0000320459
1602705A-Z
1427503A-Z

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

J R Parfitt et al.
Histopathology, 52(7), 816-823 (2008-05-23)
Gastrointestinal Kaposi's sarcoma (KS) may mimic gastrointestinal stromal tumours (GISTs) histologically. Studies have shown that KS outside the gastrointestinal (GI) tract may express CD117, an antibody usually used to support a diagnosis of GIST. The aim was to evaluate the
Robert B West et al.
The American journal of pathology, 165(1), 107-113 (2004-06-25)
We recently characterized gene expression patterns in gastrointestinal stromal tumors (GISTs) using cDNA microarrays, and found that the gene FLJ10261 (DOG1, discovered on GIST-1), encoding a hypothetical protein, was specifically expressed in GISTs. The immunoreactivity of a rabbit antiserum to
Inigo Espinosa et al.
The American journal of surgical pathology, 32(2), 210-218 (2008-01-29)
Gastrointestinal stromal tumors (GIST) occur primarily in the wall of the intestine and are characterized by activating mutations in the receptor tyrosine kinases genes KIT or PDGFRA. The diagnosis of GIST relies heavily on the demonstration of KIT/CD117 protein expression
Shigeharu Miwa et al.
Journal of gastroenterology, 43(7), 531-537 (2008-07-24)
Recently, the novel gene DOG1 has been found to be overexpressed in most gastrointestinal stromal tumors (GISTs) specifically within the field of soft tissue tumors. DOG1 might play a role in development of GISTs and have potential as a diagnostic

문서

Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

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