추천 제품
생물학적 소스
rabbit
Quality Level
100
500
결합
unconjugated
항체 형태
Ig fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
설명
For In Vitro Diagnostic Use in Select Regions (See Chart)
형태
buffered aqueous solution
종 반응성
human
포장
vial of 0.1 mL concentrate (203A-14)
vial of 0.5 mL concentrate (203A-15)
bottle of 1.0 mL predilute (203A-17)
vial of 1.0 mL concentrate (203A-16)
bottle of 7.0 mL predilute (203A-18)
제조업체/상표
Cell Marque™
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
제어
fetal liver
배송 상태
wet ice
저장 온도
2-8°C
시각화
cytoplasmic
일반 설명
Alpha-fetoprotein (AFP) is a fetal tumor-associated polypeptide of the albuminoid gene family that binds and transports molecules in addition to many other proposed functions. This secretory protein is produced by the fetal yolk sac and liver but is found only in trace amounts in adult liver. AFP expression by immunohistochemistry is seen in hepatocellular carcinoma (HCC).
Positive staining with anti-AFP is seen in hepatocytes of the fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a yolk sac carcinoma, or one of a few other tumors. Correspondingly, in conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in yolk sac tumors of gonadal and extragonadal sites, in hepatic malignancies, and in a few other neoplasms. The antigen is not denatured by most fixatives.
Positive staining with anti-AFP is seen in hepatocytes of the fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a yolk sac carcinoma, or one of a few other tumors. Correspondingly, in conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in yolk sac tumors of gonadal and extragonadal sites, in hepatic malignancies, and in a few other neoplasms. The antigen is not denatured by most fixatives.
품질
 IVD |  IVD |  IVD |  RUO |
결합
Alpha-Fetoprotein Positive Control Slides, Product No. 203S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
물리적 형태
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
제조 메모
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
기타 정보
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
법적 정보
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Manual of Diagnostic Antibodies for Immunohistology, 9-10 (1999)
Z D Goodman et al.
Cancer, 55(1), 124-135 (1985-01-01)
Combined hepatocellular-cholangiocarcinoma is a rare form of primary liver cancer showing features of both hepatocellular and biliary epithelial differentiation. In a review of 24 cases of this tumor, three histologic types were encountered. Four cases were Type I or "collision
G K Jacobsen et al.
The American journal of surgical pathology, 5(3), 257-266 (1981-04-01)
The various histologic components of 39 germ cell tumors of the testis were studied with indirect labeled immunoperoxidase technique for the presence of the following tumor-associated antigens: alpha-fetoprotein (AFP), alpha 1-antitrypsin (A1AT), chorionic gonadotropin (HCG), specific pregnancy beta 1-glycoprotein (SP1)
S H Tsung
Archives of pathology & laboratory medicine, 101(11), 572-574 (1977-11-01)
Immunofluorescence staining was applied to tissue with primary nonhepatic malignancies and/or their metastatic nodules in the liver. Tumor cells from the primary sites of two patients with carcinoma of the pancreas and one patient with Hodgkin's disease were found to
S Peyrol et al.
Digestion, 18(5-6), 351-370 (1978-01-01)
5 human cases of hepatoma have been chosen with respect to their different seric alpha-fetoprotein (alpha-FP) level and histological characters. Cells producing alpha-FP have been studied with specific horseradish-peroxidase-labelled immunoglobulins. Ultrastructural examination shows that alpha-FP is present in the cytoplasm
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