추천 제품
생물학적 소스
rabbit
Quality Level
100
500
결합
unconjugated
항체 형태
culture supernatant
항체 생산 유형
primary antibodies
클론
EPR3097Y, monoclonal
설명
For In Vitro Diagnostic Use in Select Regions (See Chart)
양식
buffered aqueous solution
종 반응성
human
포장
vial of 0.1 mL concentrate (199R-14)
vial of 0.5 mL concentrate (199R-15)
bottle of 1.0 mL predilute (199R-17)
vial of 1.0 mL concentrate (199R-16)
bottle of 7.0 mL predilute (199R-18)
제조업체/상표
Cell Marque®
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
동형
IgG
제어
Ewing’s sarcoma
배송 상태
wet ice
저장 온도
2-8°C
시각화
cytoplasmic, membranous
유전자 정보
human ... CD99(4267)
일반 설명
CD99, as detected with a variety of antibodies, is expressed by virtually almost all Ewings sarcoma and primitive peripheral neuroectodermal tumors (ES/PNET) and demonstrates strong and diffuse membranous staining. Other tumors that may show CD99 expression include neuroendocrine carcinomas, mesenchymal chondrosarcomas, solitary fibrous tumors, synovial sarcomas, vascular tumors, small round blue cell group of pediatric neoplasms, lymphoblastic lymphoma, acute myeloid leukemia, and myeloid sarcoma. However, strong and diffuse membranous reactivity for CD99 favors ES/PNET over the other diagnostic considerations. The other CD99+ tumors usually show cytoplasmic and more heterogeneous staining. Therefore, when making a final diagnostic interpretation, CD99 must be considered in a panel with other antibodies.
품질
 IVD |  IVD |  IVD |  RUO |
결합
CD99 Positive Control Slides, Product No. 199S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
물리적 형태
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
제조 메모
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
기타 정보
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
법적 정보
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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시험 성적서(COA)
Lot/Batch Number
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 126-126 (2014)
Joseph D Khoury
Advances in anatomic pathology, 12(4), 212-220 (2005-08-13)
The Ewing sarcoma family of tumors (ESFT) comprises morphologically heterogeneous tumors that are characterized by nonrandom chromosomal translocations involving the EWS gene and one of several members of the ETS family of transcription factors. The translocation t(11;22)(q24;q12) is the most
Ewing's sarcoma: new approaches to histogenesis and molecular plasticity.
W J Rettig et al.
Laboratory investigation; a journal of technical methods and pathology, 66(2), 133-137 (1992-02-01)
E J Fellinger et al.
The American journal of surgical pathology, 16(8), 746-755 (1992-08-01)
The HBA71 antigen is an M(r) 30,000/32,000 cell surface glycoprotein (p30/32MIC2), encoded by the pseudoautosomal MIC2 gene on chromosomes X and Y, that is expressed in Ewing's sarcomas. Immunohistochemical studies demonstrate a striking specificity for HBA71 among neoplasms of diverse
I M Ambros et al.
Cancer, 67(7), 1886-1893 (1991-04-01)
This study reports on the specific expression of the MIC2 gene, a pseudoautosomal gene located on the short arms of the X and Y chromosomes, on Ewing's sarcoma (ES) and peripheral primitive neuroectodermal tumor (pPNET) cells. The gene product, a
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