171R-1

CD71 (EP232) Rabbit Monoclonal Primary Antibody

• 동의어(들): TFR1, TRF, TRFR, Transferrin Receptor 1, p90, transferrin receptor (p90, CD71)
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: EP232, monoclonal
• 설명: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 형태: buffered aqueous solution
• 종 반응성: human
• 포장: vial of 0.1 mL concentrate (171R-14); vial of 0.1 mL concentrate Research Use Only (171R-14-RUO); vial of 0.5 mL concentrate (171R-15); vial of 1.0 mL concentrate (171R-16); vial of 1.0 mL concentrate Research Use Only (171R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (171R-17-RUO); vial of 1.0 mL predilute ready-to-use (171R-17); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (171R-18-RUO); vial of 7.0 mL predilute ready-to-use (171R-18)
• 제조업체/상표: Cell Marque^™
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)
• 동형: IgG
• 제어: bone marrow
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 시각화: cytoplasmic, membranous

설명

일반 설명

Transferrin receptor 1 (CD71) is expressed on placental syncytiotrophoblasts, myocytes, basal keratinocytes, hepatocytes, endocrine pancreas, spermatocytes, and erythroid precursors. The level of transferrin receptor expression is highest in early erythroid precursors through the intermediate normoblast phase, after which expression decreases through the reticulocyte phase. The maturation of erythrocytes results in loss of transferrin receptor expression. AntiCD71 is useful in identifying erythroid precursors. The high level of transferrin receptor within erythroid precursors makes anti-CD71 an excellent marker for evaluation of erythroid precursors within bone marrow biopsy specimens and shows the following features: 1) distinct membranous and cytoplasmic staining pattern, which is easily recognized in bone marrow biopsy; 2) restriction to erythroid lineage within bone marrow biopsy specimens; 3) CD71 expression decreases with the maturation of erythrocytes, with the highest level seen in early forms and the lowest level in late normoblast stage, and most importantly; 4) mature erythrocytes do not express CD71.

품질

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

결합

CD71 Positive Control Slides, Product No. 171S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide

제조 메모

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기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable