107M-2

CD7 (MRQ-56) Mouse Monoclonal Antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: MRQ-56, monoclonal
• 설명: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 형태: buffered aqueous solution
• 종 반응성: human
• 포장: vial of 0.1 mL concentrate (107M-24); vial of 0.5 mL concentrate (107M-25); bottle of 1.0 mL predilute (107M-27); vial of 1.0 mL concentrate (107M-26); bottle of 7.0 mL predilute (107M-28)
• 제조업체/상표: Cell Marque^™
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• 동형: IgG1
• 제어: lymph node, peripheral T-cell lymphoma, tonsil
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 시각화: membranous
• 유전자 정보: human ... CD7(924)

설명

일반 설명

CD7 antigen is a cell surface glycoprotein of 40 kD expressed on the surface of immature and mature T-cells as well as natural Killer (NK) cells. It is a member of the immunoglobulin gene superfamily and is the first T-cell lineage associated antigen to appear in T-cell ontogeny, being expressed in T-cell precursors (preceding CD2 expression), and in myeloid precursors, in fetal liver and bone marrow, and persisting in circulating mature T-cells. While its precise function is not known, it is suggested that the molecule functions as an Fc receptor for IgM. CD7 is the most consistently expressed T-cell antigen in lymphoblastic lymphomas/leukemias, and is therefore anti-CD7 is a useful marker in the identification of such neoplastic proliferations. In mature post-thymic T-cell neoplasms, CD7 is the most common pan-T-antigen to be aberrantly expressed, which is a useful pointer to a neoplastic T-cell process. CD7 has been shown to be immunoexpressed in 85% of mature peripheral T-cells, the majority of post-thymic T-cells, NK cells, T-cell lymphoblastic leukemia/lymphoma, acute myeloid leukemia, and chronic myelogenous leukemia, CD7 is conspicuously absent in adult T-cell leukemia/lymphoma and is not expressed in mycosis fungoides.

품질

IVD

IVD

IVD

RUO

결합

CD7 Positive Control Slides, Product No. 107S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable