09278

4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester

≥98.0% (HPLC)

• 동의어(들): 4-(Dimethylamino)azobenzene-4′-carboxylic acid N-succinimidyl ester, DABCYL-N-succinimidyl ester
• 실험식(Hill 표기법): C₁₉H₁₈N₄O₄
• CAS Number: 146998-31-4
• Molecular Weight: 366.37
• MDL number: MFCD00467415
• UNSPSC 코드: 12352108
• PubChem Substance ID: 329748752
• NACRES: NA.32

속성

• Quality Level: 100
• 분석: ≥98.0% (HPLC)
• 양식: powder
• solubility: DMF: soluble; DMSO: soluble
• 형광: λ_ex 428 nm; λ_em 453 nm
• 저장 온도: −20°C
• SMILES string: CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)C(=O)ON3C(=O)CCC3=O; CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)C(=O)ON3C(=O)CCC3=O
• InChI: 1S/C19H18N4O4/c1-22(2)16-9-7-15(8-10-16)21-20-14-5-3-13(4-6-14)19(26)27-23-17(24)11-12-18(23)25/h3-10H,11-12H2,1-2H3/b21-20+
• InChI key: IBOVDNBDQHYNJI-QZQOTICOSA-N

설명

애플리케이션

A useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies.

분석 메모

Absorption spectra shows a maximum at 453 nm (in methanol). After reaction with butylamine: max. absorption at 428 nm (Lit.)

기타 정보

N-terminal modification of peptides in automated synthesis

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)