추천 제품
분석
98% (HPLC)
Quality Level
형태
solid
색상
white to off-white
mp
162—164 °C
배송 상태
2-8°C
저장 온도
−20°C
SMILES string
O=C1N[C@@H](Cc2cnc[nH]2)C(=O)N3CCC[C@@H]13
InChI
1S/C11H14N4O2/c16-10-9-2-1-3-15(9)11(17)8(14-10)4-7-5-12-6-13-7/h5-6,8-9H,1-4H2,(H,12,13)(H,14,16)/t8-,9-/m0/s1
InChI key
NAKUGCPAQTUSBE-IUCAKERBSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Cyclo(His-Pro) is a cyclic dipeptide consisting of the amino acids histidine (His) and proline (Pro). This small peptide forms a closed loop, with histidine and proline connected through a peptide bond. It can be found naturally in certain proteins and peptides and can also be synthesized chemically. This unique molecule is related to thyrotropin-releasing hormone and has various roles in the central nervous system. It serves as a substrate for organic cation transporters, making it essential for neuroprotection. Cyclo(His-Pro) holds promise for therapeutic applications, with the potential to counteract neuroinflammation-based degenerative conditions through both oral and parenteral administration routes. It can inhibit NF-κB nuclear accumulation and influence a range of inflammatory and stress responses, making it a valuable asset in the study of cell biology, biochemical research, and neuroprotection research.
애플리케이션
Cyclo(L-His-L-Pro) is a versatile molecule and it finds application in biochemical and metabolomics research.
특징 및 장점
- Can be used in Metabolomics and Biochemical research
- High-quality compound suitable for multiple research applications
기타 정보
For additional information on our range of Biochemicals, please complete this form.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
Current protein & peptide science, 19(8), 805-812 (2018-05-01)
Protein function is dependent on assumption of the correct three-dimensional structure, achieved through the folding process. As a central element in ensuring cellular homeostasis, proteostasis i.e. the control of correct protein folding, trafficking and degradation, is a highly regulated process
Antagonism of ethanol narcosis by histidyl-proline diketopiperazine.
Nature, 268(5616), 142-144 (1977-07-14)
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