83160

L-Pyroglutamic acid

≥99.0% (T)

• 동의어(들): (S)-(−)-2-Pyrrolidone-5-carboxylic acid, (S)-5-Oxo-2-pyrrolidinecarboxylic acid
• 실험식(Hill 표기법): C₅H₇NO₃
• CAS Number: 98-79-3
• Molecular Weight: 129.11
• Beilstein: 82132
• EC Number: 202-700-3
• MDL number: MFCD00005272
• UNSPSC 코드: 12352209
• PubChem Substance ID: 57652948
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: ≥99.0% (T)
• 형태: solid
• 광학 활성: [α]20/D −10.5±1°, c = 5% in H₂O
• 광학 순도: enantiomeric ratio: ≥99:1 (GC)
• 반응 적합성: reaction type: solution phase peptide synthesis
• 무기 잔류물: ≤0.05%
• mp: 155-162 °C; 160-163 °C (lit.)
• 응용 분야: peptide synthesis
• SMILES string: OC(=O)[C@@H]1CCC(=O)N1
• InChI: 1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
• InChI key: ODHCTXKNWHHXJC-VKHMYHEASA-N

설명

애플리케이션

L-Pyroglutamic acid is used in the synthesis of:

• Nonproteinogenic amino acids such as (3S,4R)-3,4-dimethyl-L-pyroglutamic acid and (3S,4R)-3,4-dimethyl-L-glutamine.
• Chiral N-heterocyclic carbenes (NHCs) as catalysts for the asymmetric dimerization of alkylarylketenes to give the corresponding α-quaternary β-alkylidenyl-β-lactones.

It is also used in the total synthesis of (−)-stemoamide and celogentin C.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H318 - H412
• 예방조치 성명서: P273 - P280 - P305 + P351 + P338 - P501
• Hazard Classifications: Aquatic Chronic 3 - Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves