추천 제품
Quality Level
제품 라인
BioXtra
분석
≥99.0%
환경친화적 대안 제품 특성
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
불순물
≤0.01% Insoluble matter
무기 잔류물
≤0.02%
bp
235 °C (lit.)
mp
184-186 °C (lit.)
solubility
H2O: 0.5 M, clear, colorless
음이온 미량물
chloride (Cl-): ≤0.001%
sulfate (SO42-): ≤0.003%
양이온 미량물
Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%
환경친화적 대안 카테고리
, Aligned
SMILES string
OC(=O)CCC(O)=O
InChI
1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
InChI key
KDYFGRWQOYBRFD-UHFFFAOYSA-N
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일반 설명
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.
애플리케이션
Succinic acid has been used:
- in succinate dehydrogenase mitochondrial assay.
- as an internal standard in mass spectroscopy.
- as succinate dehydrogenase substrate in oxygraph analysis to measure respiration rates.
생화학적/생리학적 작용
Succinic acid is a byproduct of anaerobic fermentation in microbes. It is a dicarboxylic acid and an intermediate in Kreb′s cycle. Polymorphism in succinate dehydrogenase leads to succinate accumulation. High levels of succinate impairs 2-oxoglutarate epigenetic signalling. Succinate levels may modulate tumor progression. Succinate inhibits histone demethylation and may contribute to epigenetic changes. Succinate is crucial for interleukin-1 β (IL-1β) synthesis during inflammation and immune signalling.
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Eye Dam. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Oncometabolites: Unconventional triggers of oncogenic signalling cascades
Free Radical Biology & Medicine, 100(9), 175-181 (2016)
Screening For Isolation of Succinic Acid Producing Microbes
Biosciences, Biotechnology Research Asia, 15(2), 327-333 (2018)
Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue
Cell Cycle, 10(23), 4047-4064 (2011)
Cardiomyocyte differentiation: Experience and observations from 2 laboratories
SA heart journal, 14(2), 96-107 (2017)
Succinate: a new epigenetic hacker
Cancer Cell, 23(6), 709-711 (2013)
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