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Merck
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주요 문서

PHR1220

Supelco

Diethanolamine

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

2,2′-Iminodiethanol, Bis(2-hydroxyethyl)amine

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About This Item

Linear Formula:
HN(CH2CH2OH)2
CAS Number:
Molecular Weight:
105.14
Beilstein:
605315
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1192808

vapor density

3.6 (vs air)

vapor pressure

<0.98 atm ( 100 °C)

API family

diethanolamine

CofA

current certificate can be downloaded

autoignition temp.

689 °F

expl. lim.

10.6 %

기술

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.477 (lit.)

bp

217 °C/150 mmHg (lit.)

mp

28 °C (lit.)

density

1.097 g/mL at 25 °C (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

OCCNCCO

InChI

1S/C4H11NO2/c6-3-1-5-2-4-7/h5-7H,1-4H2

InChI key

ZBCBWPMODOFKDW-UHFFFAOYSA-N

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일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Diethanolamine is commonly used as a chemical intermediate and as a surface-active agent in agricultural products, pharmaceutical formulations and cosmetics.

애플리케이션

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Ion Mobility: TWCCSN2 value of 119.8 Å2 [M+H]+

The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.

TWCCS measurements are expected to be within 2% of this reference value.

P/N PHR1220 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.

각주

To see an example of a Certificate of Analysis for this material enter LRAC3260 in the slot below. This is an example certificate only and may not be the lot that you receive.

관련 제품

픽토그램

Health hazardCorrosionExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Oral

표적 기관

Kidney,Liver,Blood

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

280.4 °F - closed cup

Flash Point (°C)

138 °C - closed cup


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Ecotoxicological evaluation of diethanolamine using a battery of microbiotests
Zurita LJ, et al.
Toxicology in vitro, 19(7), 879-886 (2005)
S H Zeisel et al.
The Biochemical journal, 232(2), 403-408 (1985-12-01)
An understanding of the biosynthesis and metabolism of dimethylamine (DMA) is important because it is a precursor of dimethylnitrosamine (nitroso-DMA). DMA is the major short-chain aliphatic amine in human and rat urine. DMA is formed from trimethylamine (TMA), which, in
Ken-Ichi Kusumoto et al.
Journal of biomedical materials research. Part A, 91(1), 1-10 (2008-08-07)
Understanding of lipidic materials used for gene delivery system is essential for the effective design and development of potential applications in basic and therapeutic research. This study aimed to evaluate the biological activity of totally synthesized ditetradecylacetyldiethanolaminetrimethylammonium (TMA-C2-DEA-C14) as gene
Shiguo Sun et al.
Dalton transactions (Cambridge, England : 2003), (38)(38), 7969-7974 (2009-09-23)
A series of ruthenium(II) tris-bipyridyl complexes covalently linked with different amine reductants such as tripropylamine (TPrA), ethanolamine and diethanolamine for an electrochemiluminescence (ECL) system have been synthesized. Their ECL property at different working electrodes has been studied with and without
William Conway et al.
Environmental science & technology, 46(13), 7422-7429 (2012-05-25)
The kinetics of the fast reversible carbamate formation reaction of CO(2)(aq) with a series of substituted cyclic secondary amines as well as the noncyclic secondary amine diethanolamine (DEA) has been investigated using the stopped-flow spectrophotometric technique at 25.0 °C. The

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