PHL80478

Icaritin

phyproof^® Reference Substance

• 동의어(들): 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
• 실험식(Hill 표기법): C₂₁H₂₀O₆
• CAS Number: 118525-40-9
• Molecular Weight: 368.38
• MDL number: MFCD22422519
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: primary reference standard
• 제품 라인: phyproof^® Reference Substance
• 분석: ≥95.0% (HPLC)
• 제조업체/상표: PhytoLab
• 응용 분야: food and beverages
• 형식: neat
• 저장 온도: 2-8°C
• SMILES string: COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)c(C\C=C(\C)C)c3O2
• InChI: 1S/C21H20O6/c1-11(2)4-9-14-15(22)10-16(23)17-18(24)19(25)20(27-21(14)17)12-5-7-13(26-3)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
• InChI key: TUUXBSASAQJECY-UHFFFAOYSA-N

설명

일반 설명

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

생화학적/생리학적 작용

Icaritin is a component of Epimedium flavonoid isolated from Herba Epimedii, which enhances osteoblastic differentiation of mesenchymal stem cells (MSCs) while it inhibits adipogenic differentiation of MSCs by inhibiting PPAR-g pathway. Icaritin has no effect on MSCs proliferation. Also, icaritin potently inhibits chronic myeloid leukemia (CML) and breast cancer cells proliferation most likely by modulation of MAPK/ERK/JNK and JAK2/STAT3 /AKT signaling. As other flavonoids, icaritin may exert estrogen-like activities.

법적 정보

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable