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Merck
모든 사진(1)

주요 문서

O4755

Supelco

Oxantel pamoate

analytical standard

동의어(들):

1-Methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Oxantel embonate

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About This Item

실험식(Hill 표기법):
C13H16N2O · C23H16O6
CAS Number:
Molecular Weight:
604.65
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)
veterinary

형식

neat

SMILES string

CN1CCCN=C1\C=C\c2cccc(O)c2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

InChI

1S/C23H16O6.C13H16N2O/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-7,10,16H,3,8-9H2,1H3/b;7-6+

InChI key

CCOAINFUFGBHBA-UETGHTDLSA-N

일반 설명

Oxantel pamoate is a drug used in the treatment of trichuriasis which is highly effective against the helminth of Trichuris sp.

애플리케이션

Oxantel pamoate may be used as a reference standard for examining the quality of pharmaceutical dosage forms containing oxantel pamoate (OPA) by reversed-phase high-performance liquid chromatography method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Beatrice Barda et al.
The Lancet. Infectious diseases, 18(8), 864-873 (2018-06-03)
The recommended anthelmintics show low efficacy in a single-dose regimen against Trichuris trichiura. Moxidectin, a new treatment for river blindness, might complement the drug armamentarium for the treatment and control of soil-transmitted helminthiasis. However, its efficacy against T trichiura has
Intestinal protozoan and helminth infections and control of soil-transmitted helminths in Malay school children.
B Sinniah
Public health, 98(3), 152-156 (1984-05-01)
Development of oxantel tablets for pediatric clinical studies: a technical note.
Alles R, et al.
Journal of drug delivery science and technology, 23(6), 623-625 (2013)
K Peldán et al.
Scandinavian journal of infectious diseases, 14(4), 297-299 (1982-01-01)
166 patients with trichuriasis have been treated at the Department of Tropical Diseases, Aurora Hospital, Helsinki, from January 1975 to October 1979. Final results could be confirmed in 141 patients. Thiabendazole was found discouraging, because of frequent side effects and
Development and validation of a RP-HPLC method for quality control of oxantel pamoate, pyrantel pamoat and praziquantel in tablets.
Tatar E, et al.
Marmara Pharmaceutical Journal (2015)

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