모든 사진(1)
About This Item
실험식(Hill 표기법):
C11H14N4O2
CAS Number:
Molecular Weight:
234.25
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
![4-(DIMETHYLAMINO)BENZALDEHYDE [4-(DIMETHYLAMINO)BENZYLIDENE]HYDRAZONE AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/268/291/5232c253-7dd7-435c-b094-6d334239d9fb/640/5232c253-7dd7-435c-b094-6d334239d9fb.png)
Grade
analytical standard
Quality Level
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
forensics and toxicology
pharmaceutical (small molecule)
veterinary
형식
neat
저장 온도
2-8°C
SMILES string
CC1=NC(N2C(OC)=CC(C)=N2)=NC(OC)=C1
InChI
1S/C11H14N4O2/c1-7-5-9(16-3)13-11(12-7)15-10(17-4)6-8(2)14-15/h5-6H,1-4H3
InChI key
RHAXSHUQNIEUEY-UHFFFAOYSA-N
일반 설명
Mepirizole belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs), widely used in the treatment of pain and inflammation.
애플리케이션
Mepirizole may be used as an analytical reference standard for the quantification of the analyte in animal samples using ultra-high-performance liquid chromatography with tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
가장 최신 버전 중 하나를 선택하세요:
H Sekiguchi et al.
Arzneimittel-Forschung, 43(2), 134-138 (1993-02-01)
The effects of KU-1257 (N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea, CAS 120958-90-9) on gastric lesions and duodenal ulcers in rats were compared with those of various antiulcer drugs. KU-1257 prevented the formation of gastric lesions induced by necrotizing agents. The ID50 values against 0.6 N
Emilio Escrivà et al.
Inorganic chemistry, 42(25), 8328-8336 (2003-12-09)
A novel mu-pyrazolato-mu-hydroxo-dibridged copper(II) complex has been synthesized and structurally characterized: [(Cu(mepirizole)Br)2(mu-OH)(mu-pz)] (mepirizole=4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methylpyrimidine; pz=pyrazolate). The title compound crystallizes in the monoclinic system, space group P2(1)/c, with a=15.618(2) A, b=15.369(3) A, c=16.071(3) A, and beta=112.250(1) degrees. The structure is built up
K Terashima et al.
Chemical & pharmaceutical bulletin, 43(11), 2021-2023 (1995-11-01)
With a view to finding more effective antiulcer agents, a series of 2-benzylthio-5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds were synthesized and evaluated in a histamine-stimulated gastric secretion model. The sodium salt of the 2-(dimethylamino)benzylthio derivative (8) showed gastric mucosal protection and gastric
K Ueshima et al.
Digestive diseases and sciences, 39(8), 1625-1632 (1994-08-01)
The role of body temperature in the acid stimulatory mechanism by mepirizole, a duodenal ulcerogen, was investigated in urethane-anesthetized rats. Subcutaneous administration of mepirizole (60 and 200 mg/kg) increased acid secretion in a dose-dependent manner and resulted in duodenal lesions
K Amagase et al.
Arzneimittel-Forschung, 46(2), 177-184 (1996-02-01)
The effects of (+/-)-(E)-1-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-[2- [[[5-(methylamino)methyl-2-furyl] methyl]thio]ethyl]-2-(methylsulfonyl)guanidine (CAS 140695-21-2, T-593), a new histamine H2-receptor antagonist, on gastric secretion and experimental gastric and duodenal lesion/ulcer models in rats were examined. The drug administered orally or intraduodenally significantly and dose-dependently inhibited both basal
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