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![N-Benzyl-N-[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]-2,4,6-trimethylbenzenesulfonamide AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/901/010/d648acee-a7dd-4c40-958b-97d040892860/640/d648acee-a7dd-4c40-958b-97d040892860.png)
분석
≥95% (HPLC)
형태
powder
저장 온도
2-8°C
애플리케이션
Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.
생화학적/생리학적 작용
Strong ligand for retinoic acid receptor proteins
특징 및 장점
LightOx22 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx22 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
기타 정보
Chemical Equivalency 1ea=1mg
법적 정보
LightOx is a trademark of LightOx Ltd.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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문서
Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.
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