I114
p-Iodoclonidine hydrochloride
analytical standard, for drug analysis
동의어(들):
2-[(2,6-Dichloro-4-iodophenyl)imino]imidazoline hydrochloride
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C9H8Cl2IN3 · HCl
CAS Number:
Molecular Weight:
392.45
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
analytical standard, for drug analysis
Quality Level
형태
solid
기술
HPLC: suitable
gas chromatography (GC): suitable
색상
white to off-white
solubility
H2O: soluble
응용 분야
forensics and toxicology
pharmaceutical (small molecule)
veterinary
형식
neat
SMILES string
Cl[H].Clc1cc(I)cc(Cl)c1\N=C2/NCCN2
InChI
1S/C9H8Cl2IN3.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9;/h3-4H,1-2H2,(H2,13,14,15);1H
InChI key
ULCGXOSKNHMYAX-UHFFFAOYSA-N
유전자 정보
human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)
애플리케이션
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
생화학적/생리학적 작용
High affinity α2 adrenergic receptor agonist.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
가장 최신 버전 중 하나를 선택하세요:
H Zhu et al.
Life sciences, 61(19), 1973-1983 (1997-01-01)
One subtype of imidazoline receptors (IR1) is similar to alpha 2-adrenoceptors (alpha 2 AR) based on their high affinity for clonidine and related imidazoline compounds. On the other hand, IR1 possess low affinity for norepinephrine (NE) and other catecholamines. Imidazoline
N Benedetto et al.
Pathologie-biologie, 45(1), 9-18 (1997-01-01)
We investigated the effects of alpha-adrenergic on the capacity of Toxoplasma gondii to invade and proliferate in cultured human umbilical vein endothelial cells. Pretreatment of human umbilical vein endothelial cells (HUVEC) with alpha 2-adrenergic led to a high degree of
J E Piletz et al.
Journal of psychiatric research, 32(2), 55-64 (1998-08-07)
A comparison is presented between plasma catecholamine concentrations and platelet [125I]-p-iodoclonidine binding sites in 16 healthy women. Blood samples were obtained at six regularly spaced intervals over two consecutive menstrual cycles from healthy women with regular menstrual periods. Although no
M Van Dort et al.
Journal of medicinal chemistry, 30(7), 1241-1244 (1987-07-01)
The chemical synthesis of 2-[(2,6-dichloro-4-iodophenyl)imino]imidazolidine (PIC) and its radioiodinated analogue [125I]PIC is described. PIC was synthesized from 2,6-dichloroaniline in five synthetic steps. This agent displayed a high affinity for the alpha 2-adrenergic receptor (IC50 = 1.5 nM) in competitive binding
F M Heemskerk et al.
Journal of neurochemistry, 71(5), 2193-2202 (1998-11-03)
Nonadrenergic imidazoline-specific binding sites were characterized pharmacologically in crude cerebral membrane preparations, but little is known about their subcellular localization in neurons. As in the brainstem these sites are involved in cardiovascular regulation and peripherally imidazolines modulate neurotransmitter release, we
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.