추천 제품
Grade
drug standard
Quality Level
Agency
EPA 1694
농도
1.0 mg/mL in methanol
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
environmental
pharmaceutical (small molecule)
형식
single component solution
저장 온도
2-8°C
SMILES string
CN1[C@@H](CCC1=O)c2cccnc2
InChI
1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
InChI key
UIKROCXWUNQSPJ-VIFPVBQESA-N
유전자 정보
human ... CYP1A2(1544) , CYP2A6(1548)
mouse ... Cyp2a5(13087)
일반 설명
(−)-Cotinine is a major metabolite of nicotine, widely used as a biochemical marker for to evaluate the exposure to environmental tobacco smoke, for the validation of abstinence smoking and to determine the percentage of active smoking behavior.
애플리케이션
(−)-Cotinine solution has been used as a standard in the analysis of nicotine in air samples using ultra performance liquid chromatography-mass spectrometry (UPLC-MS). (−)-Cotinine may be may used as an analytical reference standard for the quantification of the analyte in biological samples using high-performance liquid chromatography technique.
(−)-Cotinine solution has been used as a standard in the analysis of nicotine in air samples using ultra performance liquid chromatography-mass spectrometry (UPLC-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
표적 기관
Eyes
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point (°F)
51.8 °F - closed cup
Flash Point (°C)
11 °C - closed cup
개인 보호 장비
Eyeshields, Faceshields, Gloves
A simple, sensitive, and rapid method for the determination of cotinine in urine by high-performance liquid chromatography with UV detection
Rabbaa-Khabbaz L, et al.
Journal of Chromatographic Science, 44(9), 535-538 (2006)
A sensitive HPLC-ESI-MS-MS method for the determination of cotinine in urine
Apinan R, et al.
Journal of Chromatographic Science, 48(6), 460-465 (2010)
Mohammad A Kaisar et al.
BMC neuroscience, 18(1), 71-71 (2017-10-13)
A sensitive, rapid and selective UHPLC-MS/MS method has been developed and validated for the quantification of Nicotine (NT) and Cotinine (CN) using Continine-d A linear response function was established for the range of concentrations 3-200 (r > 0.995) for NT and 3-600 ng/mL
Rapid and sensitive high-performance liquid chromatographic determination of nicotine and cotinine in nonsmoker human and rat urines
Oddoze.C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 708(1-2), 95-101 (1998)
Assessment of nicotine for second hand smoke exposure in some public places in Romania by UPLC-MS
Bratan A, et al.
Chemistry Central Journal, 8(1), 29-29 (2014)
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