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Merck
모든 사진(1)

주요 문서

76523

Supelco

L-Glutamine

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

동의어(들):

(S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide

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About This Item

Linear Formula:
H2NCOCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
146.14
Beilstein:
1723797
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material

Quality Level

제품 라인

TraceCERT®

grade

TraceCERT®

분석물 화학적 분류

amino acids, peptides, proteins

제조업체/상표

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

기술

HPLC: suitable
gas chromatography (GC): suitable

색상

white

mp

185 °C (dec.) (lit.)

응용 분야

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

형식

neat

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

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일반 설명

L-glutamine is found to be one of the most abundant amino acid in blood stream. It is useful in a number of biochemical processes like production of other amino acids, glucose, nucleotides, protein, and glutathione. It may also be used as a supplement to increase the intestinal villous height, maintain mucosal integrity and stimulate gut mucosal cellular proliferation. It may also find applications in the treatment of chemotherapy and radiotherapy, since it has the tendency to suppress gut and oral-toxic side effects.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Check out the entire portfolio of our amino acids certified reference materials (CRM)

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

법적 정보

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

이미 열람한 고객

Therapeutic considerations of L-glutamine: a review of the literature
LAM
Alternative Medicine Review, 4, 239-248 (1999)
Misty R Jenkins et al.
The Journal of experimental medicine, 212(3), 307-317 (2015-03-04)
Failure of cytotoxic T lymphocytes (CTLs) or natural killer (NK) cells to kill target cells by perforin (Prf)/granzyme (Gzm)-induced apoptosis causes severe immune dysregulation. In familial hemophagocytic lymphohistiocytosis, Prf-deficient infants suffer a fatal "cytokine storm" resulting from macrophage overactivation, but
Lisa A Reynolds et al.
Journal of immunology (Baltimore, Md. : 1950), 193(6), 2984-2993 (2014-08-13)
Helminth parasites remain one of the most common causes of infections worldwide, yet little is still known about the immune signaling pathways that control their expulsion. C57BL/6 mice are chronically susceptible to infection with the gastrointestinal helminth parasite Heligmosomoides polygyrus.
Kohichi Matsunaga et al.
The Journal of cell biology, 190(4), 511-521 (2010-08-18)
Autophagy is a catabolic process that allows cells to digest their cytoplasmic constituents via autophagosome formation and lysosomal degradation. Recently, an autophagy-specific phosphatidylinositol 3-kinase (PI3-kinase) complex, consisting of hVps34, hVps15, Beclin-1, and Atg14L, has been identified in mammalian cells. Atg14L
Nobuko Akiyama et al.
The Journal of experimental medicine, 211(12), 2425-2438 (2014-11-12)
Medullary thymic epithelial cells (mTECs) expressing the autoimmune regulator AIRE and various tissue-specific antigens (TSAs) are critical for preventing the onset of autoimmunity and may attenuate tumor immunity. However, molecular mechanisms controlling mTEC development remain elusive. Here, we describe the

프로토콜

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

Chromatograms

application for HPLC

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