46542

α-Estradiol

VETRANAL^®, analytical standard

• 동의어(들): 1,3,5(10)-Estratriene-3,17α-diol, 3,17α-Dihydroxy-1,3,5(10)-estratriene, Epiestradiol
• 실험식(Hill 표기법): C₁₈H₂₄O₂
• CAS Number: 57-91-0
• Molecular Weight: 272.38
• EC Number: 200-354-8
• MDL number: MFCD00064144
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329757208
• NACRES: NA.24

속성

• Grade: analytical standard
• Quality Level: 200
• 제품 라인: VETRANAL^®
• 광학 활성: [α]/D 52.0 to 56.0°, c = 1 in ethanol
• 유통기한: limited shelf life, expiry date on the label
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• 불순물: ≤2.0% water
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• SMILES string: [H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24
• InChI: 1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1
• InChI key: VOXZDWNPVJITMN-SFFUCWETSA-N

설명

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Estradiol (known as alpha Estradiol or 17 alpha Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture.17-estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer′s disease and ischemic stroke.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS08,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H341,H351,H360F,H362,H410
• 예방조치 성명서: P201 - P202 - P260 - P263 - P273 - P308 + P313
• Hazard Classifications: Aquatic Chronic 1 - Carc. 2 - Lact. - Muta. 2 - Repr. 1A
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves