437573

N,N-Dimethylformamide

ACS reagent, ≥99.8%

• 동의어(들): DMF, NSC 5356
• Linear Formula: HCON(CH₃)₂
• CAS Number: 68-12-2
• Molecular Weight: 73.09
• Beilstein: 605365
• EC Number: 200-679-5
• MDL number: MFCD00003284
• UNSPSC 코드: 12352111
• PubChem Substance ID: 24867382

속성

• Grade: ACS reagent
• Quality Level: 200
• vapor density: 2.5 (vs air)
• vapor pressure: 2.7 mmHg ( 20 °C)
• 분석: ≥99.8%
• 형태: liquid
• autoignition temp.: 833 °F
• expl. lim.: 15.2 %
• 기술: electrophoresis: suitable
• 불순물: ≤0.0005 meq/g Titr. acid; ≤0.003 meq/g Titr. base; ≤0.15% water
• 증발 잔류물: ≤0.005%
• 색상: APHA: ≤15
• refractive index: n20/D 1.430 (lit.)
• pH: 6.7
• bp: 153 °C (lit.)
• mp: −61 °C (lit.)
• solubility: water: miscible
• density: 0.944 g/mL (lit.)
• SMILES string: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
• InChI key: ZMXDDKWLCZADIW-UHFFFAOYSA-N

설명

일반 설명

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

애플리케이션

N,N-Dimethylformamide (DMF) may be used in the following processes:

• As a solvent synthesis of gold nanoparticles.
• As a solvent in capillary electrophoresis.
• Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines.
• Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea.

Solvent for many hydrophobic organic compounds.

안전성 정보

• 픽토그램: GHS02,GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H226,H312 + H332,H319,H360D
• 예방조치 성명서: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 135.5 °F - closed cup
• Flash Point (°C): 57.5 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter