추천 제품
Grade
analytical standard
Quality Level
분석
≥97.0% (HPLC)
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
pharmaceutical
형식
neat
저장 온도
−20°C
SMILES string
OC(CC1=CC(O)=CC=C1NC2=C(Cl)C=CC=C2Cl)=O
InChI
1S/C14H11Cl2NO3/c15-10-2-1-3-11(16)14(10)17-12-5-4-9(18)6-8(12)7-13(19)20/h1-6,17-18H,7H2,(H,19,20)
InChI key
VNQURRWYKFZKJZ-UHFFFAOYSA-N
일반 설명
5-Hydroxydiclofenac, a monohydroxylated metabolite of diclofenac, belongs to the class of non-steroidal anti-inflammatory compounds.29}
애플리케이션
5-Hydroxydiclofenac may be used as an analytical standard for the determination of the analyte in biological samples and wastewater by liquid chromatography (LC) based techniques.
추천 제품
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Jing Shi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 191, 1-7 (2017-10-02)
A novel flow injection chemiluminescence immunoassay for simple, sensitive and low-cost detection of diclofenac was established based on specific binding of antigen and antibody. Carboxylic resin beads used as solid phase carrier materials provided good biocompatibility and large surface-to-volume ratio
Simultaneous determination of diclofenac, its human metabolites and microbial nitration/nitrosation transformation products in wastewaters by liquid chromatography/quadrupole-linear ion trap mass spectrometry
Osorio V, et al.
Journal of Chromatography A, 1347(1), 63-71 (2014)
Klaudia Świacka et al.
Marine pollution bulletin, 141, 249-255 (2019-04-09)
Interest in the presence of pharmaceutically active compounds in the aquatic environment has been growing for over 20 years, yet very few studies deal with the metabolism of pharmaceuticals in marine organisms. In this study, the bioaccumulation under short-term conditions and
J M Monteagudo et al.
Journal of hazardous materials, 357, 457-465 (2018-06-24)
Degradation of a diclofenac aqueous solution was performed using persulfate anions activated by ultrasound. The objective of this study was to analyze different parameters affecting the diclofenac (DCF) removal reaction by the ultrasonic persulfate (US/PS) process and to evaluate the
C E Wilson et al.
Archives of toxicology, 92(6), 1953-1967 (2018-05-04)
The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached
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