36127
Climbazole
PESTANAL®, analytical standard
동의어(들):
1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C15H17ClN2O2
CAS Number:
Molecular Weight:
292.76
Beilstein:
618020
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
analytical standard
Quality Level
제품 라인
PESTANAL®
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
NMR: suitable
gas chromatography (GC): suitable
mp
96-100 °C
적합성
passes test for identity (NMR)
응용 분야
agriculture
environmental
형식
neat
SMILES string
CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n2ccnc2
InChI
1S/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3
InChI key
OWEGWHBOCFMBLP-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Climbazole is an imidazole antifungal agent, which is widely used as an active ingredient in anti-dandruff (AD) shampoos since, it inhibits the microbial growth and improves skin barrier on scalp.
애플리케이션
Climbazole may be used as a reference standard in the determination of climbazole in environmental samples and in samples of anti-dandruff shampoo using ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
추천 제품
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
법적 정보
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
이미 열람한 고객
Alex A Pérez-Rivera et al.
Mutation research, 672(1), 27-39 (2008-10-28)
Climbazole is an imidazole antifungal agent that can provide anti-dandruff benefits when incorporated into a shampoo matrix. A series of genotoxicity studies were performed to support the human safety of this azole antifungal drug. Climbazole was not mutagenic in the
W Wigger-Alberti et al.
Praxis, 90(33), 1346-1349 (2001-09-06)
Pityrosporum ovale appears to play an important role in the pathogenesis of dandruff as a symptom of seborrheic dermatitis. Climbazole is an antimycotic agent with a high in vitro and in vivo efficacy against P. ovale. In the presented work
A Schmidt
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 44(4), 193-197 (1997-06-01)
Malassezia pachydermatis is a yeast-like, mainly zoophilic fungus, also known as Malassezia canis. It can be isolated in 20-50% from normal ear cerumen specimen from dogs or cats and has an even higher prevalence in non-suppurative otitis externa in animal
Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography--tandem mass spectrometry
Chen F-Z, et al.
Analytical and Bioanalytical Chemistry, 404(10), 3175-3188 (2012)
Ultra-high-performance liquid chromatography?tandem mass spectrometry measurement of climbazole deposition from hair care products onto artificial skin and human scalp.
Chen G, et al.
Journal of Chromatography A, 1317, 155-158 (2013)
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