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Merck
모든 사진(2)

문서

34003

Supelco

HMMNI

VETRANAL®, analytical standard

동의어(들):

2-Hydroxymethyl-1-methyl-5-nitro-1H-imidazole

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About This Item

실험식(Hill 표기법):
C5H7N3O3
CAS Number:
Molecular Weight:
157.13
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

제품 라인

VETRANAL®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)

형식

neat

SMILES string

Cn1c(CO)ncc1[N+]([O-])=O

InChI

1S/C5H7N3O3/c1-7-4(3-9)6-2-5(7)8(10)11/h2,9H,3H2,1H3

InChI key

JSAQDPJIVQMBAY-UHFFFAOYSA-N

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일반 설명

HMMNI is a hydroxy metabolite of nitroimidazole antibiotics, belonging to a class of veterinary drugs with therapeutic applications in the treatment and prevention of certain bacterial and protozoal diseases in poultry and swine.
HMMNI is a major metabolite of nitroimidazole drug, dimetridazole (DMZ).

애플리케이션

HMMNI may be used as a reference standard for the determination of HMMNI in porcine liver using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
HMMNI may be used as an analytical reference standard for the determination of the analyte in:
  • Different matrices of swine using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) and ultra-performance liquid chromatography coupled to electrospray tandem mass spectrometry (UPLC-ESI-MS/MS).
  • Biological & environmental matrices using liquid chromatography with ultraviolet detection (LC-UV).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

관련 제품

제품 번호
설명
가격

픽토그램

Health hazard

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Carc. 2 - Muta. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Determination of dimetridazole in poultry tissues and eggs using liquid chromatography-thermospray mass spectrometry.
Cannavan A and Kennedy GD
Analyst, 122(9), 963-966 (1997)
G Carignan et al.
Journal - Association of Official Analytical Chemists, 71(6), 1146-1149 (1988-11-01)
A study was conducted to monitor the elimination of dimetridazole (DMZ) and its major metabolite 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI) in swine plasma and tissue, using a liquid chromatographic method with electrochemical detector sensitive to 0.5 ppb. The study consisted of 2 experiments.
Determination of 5-nitroimidazoles and corresponding hydroxy metabolites in swine kidney by ultra-performance liquid chromatography coupled to electrospray tandem mass spectrometry.
Xia Xi, et al.
Analytica Chimica Acta, 637(1-2), 79-86 (2009)
S Inghelbrecht et al.
Journal of veterinary pharmacology and therapeutics, 19(1), 62-67 (1996-02-01)
The anti-trichomonal efficacy and pharmacokinetics of dimetridazole were investigated in the homing pigeon (Columba livia). Dimetridazole was formulated for drinking water medication and as a prolonged-release tablet. To suppress a Trichomonas gallinae infection successfully, medicated drinking water containing dimetridazole (400
Analytical methodologies for the determination of nitroimidazole residues in biological and environmental liquid samples: a review.
Mahugo-Santana C, et al.
Analytica Chimica Acta, 665(2), 113-122 (2010)

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