27102

Citric acid monohydrate

puriss., meets analytical specification of Ph. Eur., BP, USP, E330, 99.5-100.5% (based on anhydrous substance), grit

• 동의어(들): 2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate
• Linear Formula: HOC(COOH)(CH₂COOH)₂ · H₂O
• CAS Number: 5949-29-1
• Molecular Weight: 210.14
• Beilstein: 4018641
• EC Number: 201-069-1
• MDL number: MFCD00149972
• UNSPSC 코드: 12352100
• PubChem Substance ID: 57648219
• NACRES: NA.21

속성

• grade: puriss.
• Quality Level: 200
• 분석: 99.5-100.5% (based on anhydrous substance)
• 형태: grit
• 품질: meets analytical specification of Ph. Eur., BP, USP, E330
• 불순물: residual solvents, complies; ≤0.0005% heavy metals (as Pb); 7.5-8.8% water (Karl Fischer)
• 무기 잔류물: ≤0.05% (as SO₄)
• pKa: (1) 3.13, (2) 4.76, (3) 6.4
• 음이온 미량물: chloride (Cl^-): ≤50 mg/kg; oxalate (as oxalic acid): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• 양이온 미량물: As: ≤1 mg/kg; Ca: ≤200 mg/kg; Cu: ≤10 mg/kg; Fe: ≤10 mg/kg; Hg: ≤1 mg/kg; Pb: ≤1 mg/kg; Zn: ≤10 mg/kg
• 적합성: complies for appearance of solution; complies for identity (IR); complies for reaction against H₂SO₄
• SMILES string: OC(CC(O)(C(O)=O)CC(O)=O)=O.O
• InChI: 1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2
• InChI key: YASYEJJMZJALEJ-UHFFFAOYSA-N

설명

일반 설명

Citric acid monohydrate is an organic acid. Its molar enthalpy of solution in water has been reported to be Δ_solH_m (298.15K, m = 0.0203molkg^-1) = (29061 ± 123)Jmol^-1

애플리케이션

Citric acid monohydrate may be used in the diltiazem hydrochloride (drug) and melt extruded Eudragit RS PO (polymer) formulations. It improves the solubility of drug in the polymer matrix. It may be used to prepare citrate buffer for use in the intravital microscopic studies of adhesion and aggregation of platelets.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 345.0 °F - closed cup
• Flash Point (°C): 173.9 °C - closed cup
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves