14131
Iopanoic acid
analytical standard
동의어(들):
2-(3-Amino-2,4,6-triiodobenzyl)butyric acid, 3-(3-Amino-2,4,6-triiodophenyl)-2-ethylpropanoic acid, Iodopanoic acid
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C11H12I3NO2
CAS Number:
Molecular Weight:
570.93
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
추천 제품
Grade
analytical standard
Quality Level
분석
≥95.0% (HPLC)
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
mp
150-156 °C
응용 분야
clinical
형식
neat
저장 온도
2-8°C
SMILES string
O=C(O)C(CC)CC1=C(I)C(N)=C(I)C=C1I
InChI
1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)
InChI key
OIRFJRBSRORBCM-UHFFFAOYSA-N
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일반 설명
Iopanoic acid is an oral cholecystographic agent, which is rich in iodine and is a potent inhibitor of 5′-deiodinase.
This radiographic contrast agent prevents the release of thyroid hormone from the thyroid gland. It also inhibits the conversion of thyroxine to triiodothyronine.
This radiographic contrast agent prevents the release of thyroid hormone from the thyroid gland. It also inhibits the conversion of thyroxine to triiodothyronine.
애플리케이션
Iopanoic acid may be used as a standard to investigate the presence and regulation of type 3 iodothyronine deiodinase in human cardiomyocytes.
추천 제품
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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이미 열람한 고객
Iopanoic acid rapidly controls type I amiodarone-induced thyrotoxicosis prior to thyroidectomy.
Bogazzi F, et al.
Journal of Endocrinological Investigation, 25(2), 176-180 (2002)
Evidence against a major role of L-thyroxine at the pituitary level: studies in rats treated with iopanoic acid (telepaque).
Obregon JM, et al.
Endocrinology, 106(6), 1827-1836 (1980)
Type 3 iodothyronine deiodinase is expressed in human induced pluripotent stem cell derived cardiomyocytes.
Nishimura K, et al.
Life Sciences (2018)
Xuehua Piao et al.
The Journal of allergy and clinical immunology, 143(1), 213-228 (2018-03-30)
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Janet L Markman et al.
Nature communications, 11(1), 1613-1613 (2020-04-03)
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