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Merck
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주요 문서

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01240585

α-Hederin

primary reference standard

동의어(들):

(3β,4α)-3-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid

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About This Item

실험식(Hill 표기법):
C41H66O12
CAS Number:
27013-91-8
Molecular Weight:
750.96
EC Number:
248-166-5
UNSPSC 코드:
85151701
NACRES:
NA.24

Grade

primary reference standard

유통기한

limited shelf life, expiry date on the label

제조업체/상표

HWI

응용 분야

food and beverages

SMILES string

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)[C@@H](CC[C@]5(C)[C@@H]4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@@]56C)C(O)=O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C41H66O12/c1-21-28(44)30(46)31(47)33(51-21)53-32-29(45)24(43)19-50-34(32)52-27-11-12-37(4)25(38(27,5)20-42)10-13-40(7)26(37)9-8-22-23-18-36(2,3)14-16-41(23,35(48)49)17-15-39(22,40)6/h8,21,23-34,42-47H,9-20H2,1-7H3,(H,48,49)/t21-,23-,24-,25+,26+,27-,28-,29-,30+,31+,32+,33-,34-,37-,38-,39+,40+,41-/m0/s1

InChI key

KEOITPILCOILGM-LLJOFIFVSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

애플리케이션

Reference Standard in the analysis of herbal medicinal products

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H302

예방조치 성명서

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
HWI02404-3
HWI02404-1
HWI02404
HWI01308-1

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문서 라이브러리 방문

H G Jeong et al.
Biochemistry and molecular biology international, 45(1), 163-170 (1998-06-23)
The protective effects of alpha-Hederin on carbon tetrachloride-induced hepatotoxicities were investigated in mice. Pretreatment with alpha-Hederin prior to the administration of carbon tetrachloride significantly prevented the increase in serum alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) activity and lipid peroxidation
Geva Feller et al.
Planta medica, 76(16), 1847-1851 (2010-06-26)
α-Hederin, a natural triterpene saponin and its derivative kalopanaxsaponin I (ksI) exhibit cytotoxicity against various cancer cell lines and IN VIVO tumors. We studied the genetic variants contributing to the activity of these two anticancer compounds. Cell lines derived from
Anne Wolf et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(2-3), 214-218 (2010-07-20)
Preparations of ivy leaves dry extract with secretolytic and bronchiolytic efficacy are widely used for the treatment of acute and chronic obstructive airway diseases. The mechanism by which ivy preparations improve lung functions is not fully understood. Here, we tested
Yang Liu et al.
Molecules (Basel, Switzerland), 15(11), 7871-7883 (2010-11-10)
Thirteen novel triterpenoid saponins, designed as amide derivatives of the natural cytotoxic saponin β-hederin, were synthesized by a stepwise glycosylation strategy. The in vitro cytotoxic activity of these compounds was evaluated against five different tumor cell lines. Most of the
Bo Wang et al.
Organic & biomolecular chemistry, 10(44), 8822-8834 (2012-10-09)
We synthesized a diosgenyl saponin bearing a unique disaccharide from the natural product β-hederin, together with twelve glycosylated derivatives and determined their cytotoxicity against five different human cancer cell lines. Most of them showed weak cytotoxicity, with the exception of
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