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SCT142

BioTracker 488 Green Microtubule Cytoskeleton Dye

Name: BioTracker 488 Green Microtubule Cytoskeleton Dye
Brand: MM

Live cell imaging microtubule dye for imaging the cytoskeleton of living cells

동의어(들):

Live cell imaging probe

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About This Item

UNSPSC 코드:

12352207

NACRES:

NA.47

추천 제품

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Sigma-Aldrich

SCT108

BioTracker 655 Red Cytoplasmic Membrane Dye

Sigma-Aldrich

SCT120

BioTracker 488 Green Nuclear Dye

Sigma-Aldrich

SCT107

BioTracker 555 Orange Cytoplasmic Membrane Dye

Sigma-Aldrich

SCT109

BioTracker 400 Blue Cytoplasmic Membrane Dye

Sigma-Aldrich

SCT136

BioTracker 488 Green Mitochondria Dye

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SCT106

BioTracker 490 Green Cytoplasmic Membrane Dye

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SCT144

BioTracker 488 Green Lipid Droplet Dye

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SCT137

BioTracker 633 Red Mitochondria Dye

Sigma-Aldrich

SCT119

BioTracker 650 Red Nuclear Dye

Sigma-Aldrich

SCT135

BioTracker 405 Blue Mitochondria Dye

기술

cell based assay: suitable

검출 방법

fluorometric

배송 상태

ambient

일반 설명

Cytoskeleton proteins such as actin and tubulin play an important role in cell structure and motility. Dysregulation of cytoskeletal proteins are also involved in cancer metastasis and disease. Taxol binds to polymerized tubulin and stabilizes microtubules, resulting in inhibition of mitosis. However, fluorescent taxol compounds like the BioTracker Microtubule Cytoskeleton dyes are less disruptive of microtubule dynamics and cell division, presumably due to lower binding affinity of the fluorescent probe compared to taxol itself.

The BioTracker Cytoskeleton Microtubule Dye is a green fluorescent cell-permeable taxol probe for imaging the microtubule cytoskeleton in live cells. It is a simple, rapid and sensitive stain that can be detected using the FITC channel. The dye is supplied with a vial of 100mM verapamil, an efflux pump inhibitor that may improve probe retention and staining in certain cell types.

Spectral Properties
Absorbance: 500nm
Emission: 515nm

애플리케이션

Live cell fluorescent imaging

Live cell imaging microtubule dye for imaging the cytoskeleton of living cells

Research Category
Cell Signaling

Research Sub Category
Live Cell Dye

성분

1) 1 vial of 50µL BioTracker 488 Green Microtubule Cytoskeleton Dye (1000X in DMSO) (CS224593)

2) 1 vial of 100µL Verapamil HCL (100mM in DMSO) (CS224592)

품질

Spectral Properties
Absorbance: 500nm
Emission: 515nm

물리적 형태

Liquid

저장 및 안정성

Store BioTracker 488 Green Microtubule Cytoskeleton Dye at 2-8ºC. Protect From Light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.