SCT086

BioTracker MitoBlue Live Cell Dye

• UNSPSC 코드: 12352207
• NACRES: NA.47

속성

• 생물학적 소스: Unknown
• 포장: vial of 1 mg
• 제조업체/상표: Millipore
• 성장 모드: N/A
• 기술: cell culture | mammalian: suitable
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

일반 설명

BioTracker MitoBlue Live Cell Dye is a synthetic bisbenzamidine derivative that selectively stains functional mitochondria while displaying low toxicity, bright blue emission, and high resistance to photobleaching in both live and fixed cells (1). It is a unique mitochondrial dye in that after initially staining mitochondria, the dye is transported to lysosomes in a time-dependent manner. This distinct staining pattern allows for monitoring and tracking the mitochondrial recycling mechanism in living cells (2). MitoBlue has been shown to be suitable for two-photon microscopy using a 740 nm two-photon excitation (TPE) wavelength and emission channel at 480 nm (2).

Spectral Properties</bold>
Absorbance: 329nm
Emission: 420nm

Reference:
1. Sa?nchez, Mateo I., et al. "MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria." ACS chemical biology 9.12 (2014): 2742-2747.
2. Sánchez, Mateo I., et al. "MitoBlue as a tool to analyze the mitochondria-lysosome communication." Scientific reports 10.1 (2020): 1-12.

애플리케이션

Purity >97% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.

특징 및 장점

Live cell imaging dye that stains functional mitochondria and tracks the mitochondrial degradation process and transport to lysosomes.

물리적 형태

Lyophilized. Yellow solid.

저장 및 안정성

Store at -20°C, desiccate and protect from light.Note: Centrifuge vial briefly to collect contents at bottom of vial before opening

기타 정보

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable