SCC224

YUMM 1.1 Mouse Melanoma Cell Line

Mouse

• 동의어(들): Yale University Mouse Melanoma 1.3 cell line, Yale University Mouse Melanoma cell line
• UNSPSC 코드: 41106514
• NACRES: NA.81

속성

• product name: YUMM 1.1 Mouse Melanoma Cell Line,
• 생물학적 소스: mouse
• Quality Level: 100
• 포장: vial of ≥1X10⁶ vial
• 제조업체/상표: Millipore
• 기술: cell culture | mammalian: suitable
• 배송 상태: liquid nitrogen
• 저장 온도: −196°C

설명

일반 설명

YUMM1.1 cells are syngeneic with the immunocompetent C57BL/6 mouse background and retain genetic markers of the Braf/Pten mouse models, characterized by activation of Braf and inactivation of Pten and Cdkn2a.

애플리케이션

• Each vial contains >1X10⁶ viable cells.
• YUMM1.1 cells are tested negative for infectious diseases by a Mouse Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are verified to be of mouse origin and negative for inter-species contamination from rat, chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.

특징 및 장점

The YUMM cell lines recapitulate genetic drivers found in many human melanomas. YUMM1.1 is driven by Braf activation, Pten/Cdkn2a inactivation, and is highly tumorigenic in vivo.

표적 설명

The promise of immune-based therapies in cancer and recent progress in successful application of these approaches has confirmed the utility of immunocompetent models for evaluation of the immune system response to cancer cells. Genetically engineered mou

저장 및 안정성

YUMM1.1 cells should be stored in liquid nitrogen until use. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

기타 정보

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact l

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable