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Merck
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Key Documents

OP66

Sigma-Aldrich

Anti-Rb (Ab-5) Mouse mAb (LM95.1)

liquid, clone LM95.1, Calbiochem®

동의어(들):

Anti-Retinoblastoma Associated Protein, Anti-pp105

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About This Item

UNSPSC 코드:
12352203

생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

LM95.1, monoclonal

형태

liquid

포함

≤0.1% sodium azide as preservative

종 반응성

human

제조업체/상표

Calbiochem®

저장 조건

do not freeze

동형

IgG1

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... RB1(5925)

일반 설명

Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-1 mouse myeloma cells. Recognizes the ~105 kDa Rb protein.
Recognizes the ~105 kDa Rb protein. Sold under license of U.S. Patent 5,853,988 and corresponding patents.
This Anti-Rb (Ab-5) Mouse mAb (LM95.1) is validated for use in Immunoblotting, Paraffin Sections for the detection of Rb (Ab-5).

면역원

Epitope: within a 56 kDa C-terminal fragment
Human
recombinant, human Rb

애플리케이션

Immunoblotting (1 µg/ml; see application references)

Paraffin Sections (3 µg/ml, see comments and application references)

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Standard Handling (A)

물리적 형태

In 50 mM sodium phosphate buffer, 0.2% gelatin.

분석 메모

Negative Control
Saos cells
Positive Control
ML-1 cells or normal colon tissue

기타 정보

Dyson, N., et al. 1992. J. Virol.66, 4606.
Dyson, N., et al. 1990. J. Virol.64, 1353.
Horowitz, J.M., et al. 1989. Science243, 937.
Whyte, P., et al. 1988. Nature334, 124.
Klein, G. 1987. Science238, 1539.
Lee, W.H., et al. 1987. Science235, 1394.
Lee, W.H., et al. 1987. Nature329, 642.
Knudson, A.G. 1971. Proc. Natl. Acad. Sci. USA68, 820.
Pre-treatment with heat or pressure cooker may improve staining of some tissue specimens; this should be determined for each specimen. Antibody should be titrated for optimal results in individual systems.

법적 정보

Sold under license of U.S. Patent 5,853,988 and corresponding patents.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Abstracts from USCAP 2019: Genitourinary Pathology (including renal tumors) (776-992).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 32(Suppl 2), 1-173 (2019-03-20)
Alessandro Bertolo et al.
Scientific reports, 10(1), 19084-19084 (2020-11-07)
Mesenchymal stromal cells (MSC) are used in cell therapy, but results depend on the unknown quality of cell populations. Extended culture time of MSC increases their senescent levels, leading to a critical loss of cell fitness. Here, we tested the
Ching-Wen Tsai et al.
Artificial cells, nanomedicine, and biotechnology, 46(8), 1852-1863 (2017-10-31)
This study evaluated the effect of chitosan, poly vinyl alcohol (PVA) and poly (2-hydroxyethyl methacrylate) (pHEMA) on delaying the human fibroblast senescence. Cells could form suspending multicellular spheroids on these biomaterials, but only chitosan was capable of decreasing the SA
Tao Wei et al.
mBio, 12(4), e0227721-e0227721 (2021-09-02)
The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous cell carcinomas in laboratory mice.
Hsi-Hsien Hsieh et al.
Journal of cell science, 130(19), 3272-3281 (2017-08-11)
SerpinB2 is a serine protease inhibitor also known as plasminogen activator inhibitor type 2 (PAI-2). It has been well documented that serpinB2 is an inhibitor of urokinase plasminogen activator (uPA) and tissue plasminogen activator (tPA). Interestingly, serpinB2 levels are increased

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