MAIPNTR10

Multiscreen^® 96 well Plate, hydrophobic PVDF membrane

pore size 0.45 μm, non-sterile

• 동의어(들): 96-Well PVDF Plate, Hydrophobic 96-Well Plate, PVDF 96-Well Plate
• UNSPSC 코드: 41104923
• eCl@ss: 32039006
• NACRES: NB.22

속성

• material: PVDF membrane (hydrophobic); acrylic ; flat bottom wells
• Quality Level: 400
• 설명: This clear 96 well filter plate has a Hydrophobic PVDF membrane used for PAMPA.
• 무균: non-sterile
• 제품 라인: MultiScreen^®
• 특징: hydrophobic; lid
• 제조업체/상표: MultiScreen^®
• 파라미터: 50-250 μL sample volume (per well)
• 기술: parallel artificial membrane permeation assay (PAMPA): suitable
• 플레이트 크기: 96 wells
• 웰 최대 용적: 300 μL
• 작업 용적: 50-250 μL
• 기질: Immobilon^®-P
• 공극 크기: 0.45 μm pore size
• 결합 유형: high binding surface
• 배송 상태: ambient

설명

일반 설명

Filter Code: IP

Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput

Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.

애플리케이션

Research Category
Assays

Protein

물리적 형태

Color Code: Clear

기타 정보

Automation Compatible: No

법적 정보

Immobilon is a registered trademark of Merck KGaA, Darmstadt, Germany

MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany