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Merck
모든 사진(1)

문서

MABS36

Sigma-Aldrich

Anti-ODC1 Antibody, clone CPTC-ODC1-2

clone CPTC-ODC1-2, from mouse

동의어(들):

ornithine decarboxylase 1, ornithine decarboxylase

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

CPTC-ODC1-2, monoclonal

종 반응성

human

기술

western blot: suitable

동형

IgG2aκ

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... ODC1(4953)

일반 설명

Ornithine decarboxylase (ODC1) is the first enzyme in polyamine synthesis and is mandatory for normal growth and is increased in many types of cancers. ODC1 has been shown to suppress the fmc1 deletion in yeast and restores healthy respiratory growth. ODC1 may play a role in promoting DNA synthesis in hepatocytes.

면역원

Full length of recombinant protein corresponding to human ODC1.

Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program.

애플리케이션

Research Category
Signaling
This Anti-ODC1 Antibody, clone CPTC-ODC1-2 is validated for use in WB for the detection of ODC1.

품질

Evaluated by Western Blot in MCF-7 cell lysate.

Western Blot Analysis: 10 µg/mL of this antibody detected ODC1 on 10 µg of MCF-7 cell lysate.

표적 설명

~51 kDa observed. A band at ~100 kDa may be observed in some lysates and may be the homodimer of this protein.

물리적 형태

Format: Purified
Protein G
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
MCF-7 cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Guillaume N Fiches et al.
PLoS pathogens, 18(4), e1010503-e1010503 (2022-04-30)
Polyamines are critical metabolites involved in various cellular processes and often dysregulated in cancers. Kaposi's sarcoma-associated Herpesvirus (KSHV), a defined human oncogenic virus, leads to profound alterations of host metabolic landscape to favor development of KSHV-associated malignancies. In our studies
Milind D Chalishazar et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(16), 5107-5121 (2019-06-06)
Small-cell lung cancer (SCLC) has been treated clinically as a homogeneous disease, but recent discoveries suggest that SCLC is heterogeneous. Whether metabolic differences exist among SCLC subtypes is largely unexplored. In this study, we aimed to determine whether metabolic vulnerabilities

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