MABN92-AF555

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 555 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR^™ 555

• 동의어(들): Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: ALEXA FLUOR^™ 555
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: 20A12.1, monoclonal
• 종 반응성: rat, mouse, human
• 기술: immunohistochemistry: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_001614
• UniProt 수납 번호: P55008
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... AIF1(199)

설명

일반 설명

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

면역원

Linear peptide corresponding to a human Iba1/AIF1 sequence.

애플리케이션

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 555 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.

품질

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:150 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

표적 설명

~17 kDa observed

물리적 형태

Protein G Purified

Purified mouse antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

법적 정보

ALEXA FLUOR is a trademark of Life Technologies

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable