MABN118

Anti-Limk1 Antibody, clone 6C3.1| MABN118

clone 6C3.1, from mouse

• 동의어(들): LIM domain kinase 1, LIMK-1, Lim kinase 1
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 6C3.1, monoclonal
• 종 반응성: human
• 기술: immunohistochemistry: suitable; western blot: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_002305
• UniProt 수납 번호: P53667
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... LIMK1(3984)

설명

일반 설명

LIM Kinase 1 (LIMK1) is a protein kinase that plays an important role in cellular functions like cell motility and growth cone actin dynamics. LIMK1 contains one PDZ domain and two LIM domains which mediate protein to protein inteactions. It is widely expressed in the adult and fetal nervous system with the highest levels being found in the cerebral cortex. Mutations in LIMK1 have been associated with cardiovascular and musculo-skeletal abnormalities.

면역원

GST-tagged recombinant protein corresponding to human Limk1.

애플리케이션

Detect Limk1 using this Anti-Limk1 Antibody, clone 6C3.1 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Limk1 in human thalamus and human cerebral cortex tissue.

품질

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Limk1 in 10 µg of human cortex tissue lysate.

표적 설명

~72 kDa observed

물리적 형태

Format: Purified

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable