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Merck
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Key Documents

MABC531

Sigma-Aldrich

Anti-Somatotropin/GH1 Antibody, clone 1H1.1

clone 1H1.1, from mouse

동의어(들):

Somatotropin, Growth hormone, GH, GH-N, Growth hormone 1, Pituitary growth hormone, -Somatotropin/GH1

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.43

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

1H1.1, monoclonal

종 반응성

human

기술

western blot: suitable

동형

IgG1κ

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... GH1(2688)

관련 카테고리

일반 설명

Somatotropin (UniProt P01241; also known as GH, GH-N, Growth hormone 1, hGH-N, Pituitary growth hormone) is encoded by the GH1 (also known as GH, GHN, IGHD1B) gene (Gene ID 8856) in human. Somatotropin is a peptide hormone that plays an important role in growth control by inducing IGF-1 secretion in liver and other tissues. It stimulates myoblast differentiation and proliferation, as well as amino acids uptake and protein synthesis in muscle and other tissues. Acromegaly is a rare endocrine syndrome caused by a GH-secreting pituitary adenoma. Acromegaly may also be rarely associated with a hypothalamic or an ectopic GH-releasing hormone-producing tumor.

특이성

Expected to react with isoforms 1, 3, and 4. Reactivity to isoforms 2 and 5 have not been tested.

면역원

GST-tagged recombinant protein corresponding to human Somatotropin/GH1.

애플리케이션

Anti-Somatotropin/GH1 Antibody, clone 1H1.1 is an antibody against Somatotropin/GH1 for use in Western Blotting.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

품질

Evaluated by Western Blotting in human pituitary tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Somatotropin/GH1 in 10 µg of human pituitary tissue lysate.

표적 설명

~25 kDa observed. This protein has several isoforms from ~20-25 kDa

물리적 형태

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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