MAB1572

Anti-Parvalbumin Antibody

ascites fluid, clone PARV-19, Chemicon^®

• 동의어(들): Anti-D22S749
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: PARV-19, monoclonal
• 종 반응성: feline, rabbit, goat, frog, fish, human, pig, bovine, rat, mouse, canine
• 제조업체/상표: Chemicon^®
• 기술: immunocytochemistry: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• 동형: IgG1
• NCBI 수납 번호: NM_002854.2
• UniProt 수납 번호: P20472
• 배송 상태: dry ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PVALB(5816)

설명

일반 설명

Parvalbumin is a calcium binding albumin protein. It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is present in GABAergic interneurons in the nervous system, predominantly expressed by chandelier and basket cells in the cortex.

특이성

Parvalbumin. The antibody will react with parvalbumin from brain and muscle. By immunoblot it recognizes a protein of 12 kDa. The antibody is directed against an epitope at the first Ca+2-binding site and specifically stains the Ca+2 -bound form of parvalbumin.

면역원

Parvalbumin purified from frog muscle

애플리케이션

Anti-Parvalbumin Antibody is an antibody against Parvalbumin for use in IC, IH(P) & WB.

Immunohistochemistry:
A previous lot was used by indirect immunoperoxidase at 1:1,000-1:2,000 dilution. The antibody works on formalin fixed, paraffin embedded tissue sections of rat cerebellum from a previous lot. Fixation does not appear to affect MAB1572’s ability to detect parvalbumin.

Immunocytochemistry:
A previous lot of this antibody was used on cultured neurons.

Optimal working dilutions must be determined by the end user.

Research Category
Neuroscience

Research Sub Category
Signaling Neuroscience

품질

Routinely evaluated by Western Blot on mouse brain lysate.

Western Blot Analysis:
1:1000 dilution of this lot detected Parvalbumin on 10 μg of mouse brain lysate.

표적 설명

12 kDa

물리적 형태

Ascites mouse monoclonal IgG1 liquid

Unpurified

저장 및 안정성

Stable for 1 year at -20ºC from date of receipt.

분석 메모

Control
Brain tissue, Cultured neurons

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable