MAB8879

Anti-Cdk4 Antibody, clone DCS-35

clone DCS-35, Chemicon^®, from mouse

• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 클론: DCS-35, monoclonal
• application: IF; IHC; IP; WB; activity assay
• 종 반응성: mouse, pig, rat, human
• 기술: activity assay: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• citations: 10

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: DCS-35, monoclonal
• 종 반응성: mouse, pig, rat, human
• 제조업체/상표: Chemicon^®
• 기술: activity assay: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NM_000075.2
• UniProt 수납 번호: P11802
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CDK4(1019) ; rat ... Cdk4(94201)

설명

일반 설명

The prototype of the cdk family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression.

특이성

Recognizes a 34 kDa protein identified as p34 or cyclin-dependent kinase 4 (cdk4). It shows no cross-reaction with other cdks.

면역원

Raised against purified recombinant cdk4 protein.

애플리케이션

Detect Cdk4 with Anti-Cdk4 Antibody, clone DCS-35 (Mouse Monoclonal Antibody), that has been shown to work in IF, IP, EA, WB & IHC.

Immunofluorescence

Immunoprecipitation: excellent for coprecipitation of D-type cyclins bound to cdk4.

Western Blotting: 2-4 ug/mL

Kinase Assay

The prototype of the cdk family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression.

Optimal working dilutions must be determined by the end user.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

결합

Replaces: MABE548

물리적 형태

Format: Purified

Purified immunoglobulin. Liquid containing 10 mM PBS, pH 7.4 with 0.2% BSA and 0.09% sodium azide.

저장 및 안정성

Maintain liquid material at 2-8°C for up to 24 months.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids