추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
ascites fluid
항체 생산 유형
primary antibodies
클론
monoclonal
종 반응성
human, mouse, rat
제조업체/상표
Chemicon®
기술
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
동형
IgG2b
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... OLIG1(116448)
rat ... Olig1(60394)
일반 설명
Olig-1 is a bHLH transcription factor that is expressed by oligodendrocytes in the brain where it promotes oligodendrocyte formation and maturation. Olig1 cooperates with Olig2 to establish the pMN domain of the embryonic neural tube.
특이성
Oligodendrocyte marker Olig1. The antibody typically stains cell in either the cytoplasm or nucleus depending on cell type. Staining will be present in the nucleus of remyelinating oligodendrocytes.
면역원
Fusion protein from mouse Olig1.
애플리케이션
Anti-Olig1 Antibody is an antibody against Olig1 for use in WB, IC, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
물리적 형태
Liquid ascites fluid.
저장 및 안정성
Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
분석 메모
Control
Positive control: Corpus callosium Negative control: skin or non-neural organs
Positive control: Corpus callosium Negative control: skin or non-neural organs
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Olga Britanova et al.
Developmental biology, 298(1), 299-311 (2006-08-12)
Projection neurons of the developing cerebral cortex are generated in the cerebral ventricular zone and subsequently move to the developing cortical plate via radial migration. Conversely, most inhibitory interneurons originate in the ganglionic eminences and enter the developing cortical plate
Mario Marotta et al.
Stem cell research, 22, 33-42 (2017-06-05)
Despite benefits of prenatal in utero repair of myelomeningocele, a severe type of spina bifida aperta, many of these patients will still suffer mild to severe impairment. One potential source of stem cells for new regenerative medicine-based therapeutic approaches for
Hong Zhao et al.
Molecular medicine reports, 20(5), 4603-4611 (2019-11-09)
The differentiation and maturation of oligodendrocyte precursor cells (OPCs) is important for remyelination in the central nervous system. Nevertheless, this process is often limited and incomplete in ischemic injury. Oligodendrocyte transcription factor 1 (Olig1) is important for the maturation of OPCs and
Disruption of glial cell development by Zika virus contributes to severe microcephalic newborn mice.
Cui Li et al.
Cell discovery, 4, 43-43 (2018-08-08)
The causal link between Zika virus (ZIKV) infection and microcephaly has raised alarm worldwide. Microglial hyperplasia, reactive gliosis, and myelination delay have been reported in ZIKV-infected microcephalic fetuses. However, whether and how ZIKV infection affects glial cell development remain unclear.
Jenna J Boulanger et al.
Frontiers in neuroscience, 11, 143-143 (2017-04-13)
Key Points Oligodendrocyte precursor cells express doublecortin, a microtubule-associated protein.Oligodendrocyte precursor cells express doublecortin, but at a lower level of expression than in neuronal precursor.Doublecortin is not associated with a potential immature neuronal phenotype in Oligodendrocyte precursor cells. Oligodendrocyte precursor
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