MAB5258A4

Anti-Synaptophysin Antibody, clone SY38, Alexa Fluor^™ 488 Conjugate

clone SY38, from mouse, ALEXA FLUOR^™ 488

• 동의어(들): Synaptophysin, Major synaptic vesicle protein p38
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: ALEXA FLUOR^™ 488
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: SY38, monoclonal
• 종 반응성: mouse, human
• 종 반응성(상동성에 의해 예측): bovine (immunogen homology)
• 기술: immunohistochemistry: suitable
• 동형: IgG1
• NCBI 수납 번호: NP_776388
• UniProt 수납 번호: P20488
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SYP(6855)

설명

일반 설명

Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. The localization and ubiquitous expression of this protein in neuronal tissue makes it an excellent marker for neurons and neuroendocrine tumors. The gene for this protein is located on the X chromosome (Xp11.23-p11.22). The exact function of the protein is unknown: it interacts with the essential synaptic vesicle protein synaptobrevin, but when the synaptophysin gene is experimentally inactivated in animals, they still develop and function normally.

특이성

This antibody reacts with presynaptic vesicles of cerebral and spinal neurons, of neuromuscular endplates and with the retina of man, cow, rat and mouse. It also reacts with vesicles of adrenal medulla and islet cells.

면역원

Vesicular fraction of bovine brain

애플리케이션

Anti-Synaptophysin Antibody, clone SY38, Alexa Fluor 488 Conjugate detects level of Synaptophysin & has been published & validated for use in IH.

Research Category
Neuroscience

Research Sub Category
Neuronal & Glial Markers

품질

Evaluated by Immunohistochemistry in adult mouse brain tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Synaptophysin in adult mouse brain tissue.

표적 설명

The unconjugated parent antibody (Cat. No. MAB5258) has an observed molecular weight at ~38 kDa

물리적 형태

Protein G purified

Purified mouse monoclonal IgG1κ conjugated to Alexa Fluor^™ 488 in buffer containing 15 mg/ml BSA with 0.1% sodium azide.

저장 및 안정성

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

분석 메모

Control
Adult mouse brain tissue

기타 정보

Uncongugated antibody (MAB5258) is shown to work on Rat.

법적 정보

ALEXA FLUOR is a trademark of Life Technologies

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable