추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
ascites fluid
항체 생산 유형
primary antibodies
클론
1H4, monoclonal
종 반응성
human, mouse
제조업체/상표
Chemicon®
기술
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
동형
IgG1
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... PPARG(5468)
일반 설명
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: a, b and g. PPARg stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs can bind to DNA only as a heterodimer with the retinoid X receptor (RXR).
특이성
Reacts with human PPAR gamma2. The antibody also reacts with PPAR gamma1 due to immunogen sequence homology. The immunogen shows no homology with PPAR alpha or PPAR beta.
면역원
Epitope: isoform 1&2
Synthetic peptide from amino acids 107-121 of human PPAR gamma2.
애플리케이션
Anti-PPAR γ Antibody, isoform 1&2 is a Mouse Monoclonal Antibody for detection of PPAR gamma also known as Peroxisome Proliferator Activated Receptor γ & has been validated in ELISA, ICC & WB.
표적 설명
67 kDa
분석 메모
Control
THP-1 cell lysate, 3T3-L1 cell lysate or U-937 cell lysate
THP-1 cell lysate, 3T3-L1 cell lysate or U-937 cell lysate
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Younho Han et al.
Scientific reports, 6, 35655-35655 (2016-10-19)
Osterix is a novel bone-related transcription factor involved in osteoblast differentiation, and bone maturation. Because a reciprocal relationship exists between adipocyte and osteoblast differentiation of bone marrow derived mesenchymal stem cells, we hypothesized that Osterix might have a role in
Regional anatomic and age effects on cell function of human adipose-derived stem cells.
Bret M Schipper,Kacey G Marra,Wei Zhang,Albert D Donnenberg,J Peter Rubin
Annals of Plastic Surgery null
Qi Tang et al.
International journal of molecular medicine, 40(3), 713-720 (2017-07-22)
Adipose tissue engraftment has become a well-established therapy in plastic and reconstructive surgery used to restore age-related or injury-related soft tissue loss. However, the unpredictable absorption rates limit its further application. Some clinicians have noted that more optimal aesthetic results
Yifeng Jin et al.
Scientific reports, 6, 34661-34661 (2016-10-04)
Conformational change in helix 12 can alter ligand-induced PPARγ activity; based on this reason, isoquinolinoquinazolinones, structural homologs of berberine, were designed and synthesized as PPARγ antagonists. Computational docking and mutational study indicated that isoquinolinoquinazolinones form hydrogen bonds with the Cys285
William P Cawthorn et al.
Bone, 50(2), 477-489 (2011-08-30)
Wnt10b is an established regulator of mesenchymal stem cell (MSC) fate that inhibits adipogenesis and stimulates osteoblastogenesis, thereby impacting bone mass in vivo. However, downstream mechanisms through which Wnt10b exerts these effects are poorly understood. Moreover, whether other endogenous Wnt
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.