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Merck
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Key Documents

MAB3775

Sigma-Aldrich

Anti-Cdc20 Antibody, clone AR12

clone AR12, Chemicon®, from mouse

동의어(들):

Cell Division Cycle Protein 20 Homolog, p55cdc

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

AR12, monoclonal

종 반응성

human

제조업체/상표

Chemicon®

기술

immunofluorescence: suitable
immunoprecipitation (IP): suitable

동형

IgG1

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... CDC20(991)

특이성

Recognizes human Cdc20

면역원

Human Cdc20 recombinant protein

애플리케이션

Anti-Cdc20 Antibody, clone AR12 is a Mouse Monoclonal Antibody for detection of Cdc20 also known as Cell Division Cycle Protein 20 Homolog p55cdc & has been validated in IF & IP.
Immunofluorescence

Immunoprecipitation

Optimal working dilutions must be determined by end user.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

물리적 형태

Format: Purified
Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.

저장 및 안정성

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

L Sironi et al.
The EMBO journal, 20(22), 6371-6382 (2001-11-15)
Mad2 is a key component of the spindle checkpoint, a device that controls the fidelity of chromosome segregation in mitosis. The ability of Mad2 to form oligomers in vitro has been correlated with its ability to block the cell cycle
James Bancroft et al.
Molecular biology of the cell, 31(21), 2315-2330 (2020-08-07)
Ubiquitin-dependent proteolysis of cyclin B and securin initiates sister chromatid segregation and anaphase. The anaphase-promoting complex/cyclosome and its coactivator CDC20 (APC/CCDC20) form the main ubiquitin E3 ligase for these two proteins. APC/CCDC20 is regulated by CDK1-cyclin B and counteracting PP1
Gang Zhang et al.
Nature communications, 8, 15822-15822 (2017-06-13)
Proper segregation of chromosomes depends on a functional spindle assembly checkpoint (SAC) and requires kinetochore localization of the Bub1 and Mad1/Mad2 checkpoint proteins. Several aspects of Mad1/Mad2 kinetochore recruitment in human cells are unclear and in particular the underlying direct
Mark D Gurden et al.
Cancer research, 75(16), 3340-3354 (2015-07-24)
Acquired resistance to therapy is perhaps the greatest challenge to effective clinical management of cancer. With several inhibitors of the mitotic checkpoint kinase MPS1 in preclinical development, we sought to investigate how resistance against these inhibitors may arise so that

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