추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
41-1E5, monoclonal
종 반응성
rabbit, human
제조업체/상표
Chemicon®
기술
ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
동형
IgG2aκ
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... MMP1(4312)
특이성
Specifically reacts with precursor and active forms of human MMP-1.
면역원
Epitope: a.a. 332-350 hMMP1
Syntheic peptide aa332-350 of hMMP-1
애플리케이션
Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5 detects level of MMP-1 & has been published & validated for use in ELISA, IH(P) & WB.
Immunoblotting:
Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended
ElA
Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended
ElA
표적 설명
52 kDa
결합
Replaces: 04-1122
물리적 형태
Format: Purified
Liquid in 0.1 M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine Serum albumin.
분석 메모
Control
Cervical carcinoma
SKBr-3 cell lysate
Cervical carcinoma
SKBr-3 cell lysate
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts.
Andreea M Bujor,Sashidar Nakerakanti,Erin Morris,Faye N Hant,Maria Trojanowska
Experimental Dermatology null
Immunohistochemical demonstration of collagenase and tissue inhibitor of metalloproteinases (TIMP) in synovial lining cells of rheumatoid synovium
Okada, Y. et al.
Virchows Archiv. B, Cell Pathology Including Molecular Pathology, 59, 305-312 (1990)
Cdc42 downregulates MMP-1 expression by inhibiting the ERK1/2 pathway.
Deroanne, CF; Hamelryckx, D; Ho, TT; Lambert, CA; Catroux, P; Lapiere, CM; Nusgens, BV
Journal of Cell Science null
A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 1 (interstitial collagenase) using monoclonal antibodies
Zhang, J. et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 219, 1-14 (1993)
Carine Strup-Perrot et al.
World journal of gastroenterology, 11(40), 6312-6321 (2006-01-19)
To investigate their expression and activity in the rat ileum after exposure to ionizing radiation along with that of the cellular effectors and molecular mediators involved in the regulation of MMPs. Rats were exposed to a single 10-Gy dose of
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