MAB2636

Anti-SERCA2 Antibody, clone IID8

clone IID8, from mouse

• 동의어(들): Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SR Ca(2+)-ATPase 2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic r
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: IID8, monoclonal
• 종 반응성: human
• 기술: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_001003214
• UniProt 수납 번호: O46674
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ATP2A2(488)

설명

일반 설명

The sarcoplasmic reticulum of striated muscle is a specialized intracellular membrane system that plays a critical role in the contraction and relaxation of muscle. The sarco/endoplasmic reticulum Ca2+ ATPases (SERCAs) mediate Ca2+ uptake into intracellular stores. SERCA mediated Ca2+ uptake induces and maintains muscular relaxation. SERCA1 is expressed in fast-twitch muscles, whereas SERCA2 is expressed in cardiac and slow-twitch muscles. SERCA2 plays an important part in regulating cardiac contractile function.

특이성

The antibody recognizes SERCA2.

면역원

Epitope: Unknown

Purified canine cardiac sarcoplasmic reticulum.

애플리케이션

Anti-SERCA2 Antibody, clone IID8 is an antibody against SERCA2 for use in WB, IC, IH.

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Eizema, 2007).

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Cytoskeletal Signaling

품질

Evaluated by Western Blot in HEK293 cell lysate.

Western Blot Analysis: 0.5 µg/ml of the antibody detected SERCA2 in 10 µg of HEK293 cell lysate.

표적 설명

~ 110 kDa

물리적 형태

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
HEK293 cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable