추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified antibody
클론
monoclonal
종 반응성
rat, mouse, human
제조업체/상표
Neuro-Chrom
기술
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
동형
IgG1
배송 상태
wet ice
타겟 번역 후 변형
unmodified
일반 설명
Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a monoclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse fixations, cell culture and immunohistochemistry protocols, including archival brain tissue, giving researchers a convienent and specific qualitative and quantitative tool for studying neuronal morphology.
특이성
Cat. # MAB2300 is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
Reactivity with other species has not been determined.
면역원
Epitope: Whole Neuron Marker
애플리케이션
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
품질
Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry.
물리적 형태
Blended monoclonal antibody cocktail in PBS with 0.05% NaN3
Format: Purified
저장 및 안정성
Maintain at 2-8°C for up to 1 year from date of receipt.
분석 메모
Control
Rat E18 cortex primary neurons
Rat E18 cortex primary neurons
법적 정보
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Nature immunology, 19(5), 1-7 (2018-04-18)
The cytokine transforming growth factor-β (TGF-β) regulates the development and homeostasis of several tissue-resident macrophage populations, including microglia. TGF-β is not critical for microglia survival but is required for the maintenance of the microglia-specific homeostatic gene signature1,2. Under defined host
Short-term fasting induces profound neuronal autophagy.
Autophagy null
PloS one, 12(11), e0188605-e0188605 (2017-11-28)
Our recent study indicated that vitamin D and its receptors are important parts of the amyloid processing pathway in neurons. Yet the role of vitamin D receptor (VDR) in amyloid pathogenesis is complex and all regulations over the production of
Neurochemical research, 45(3), 663-671 (2019-11-30)
The myelin proteolipid protein gene (PLP1) encodes the most abundant protein in CNS myelin. Expression of the gene must be strictly regulated, as evidenced by human X-linked leukodystrophies resulting from variations in PLP1 copy number, including elevated dosages as well
Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by ?7 nicotinic receptor agonist.
Stem Cells Translational Medicine null
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