추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
ascites fluid
항체 생산 유형
primary antibodies
클론
4C7, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
동형
IgG2a
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... LAMA2(3908)
특이성
Reacts with the globular domain of the alpha5 chain of intact laminin and blocks the neurite stimulating activity of laminin. This antibody was originally thought to recognize laminin alpha 1 or A, but further characterization has confirmed its specificity for the laminin alpha 5 chain [see Tiger, C.F. (1997) J. Biol. Chem. 272: 28590].
애플리케이션
Anti-Laminin α5 Antibody, clone 4C7 is an antibody against Laminin α5 for use in ELISA, IH & IP.
ELISA (50% maximal binding to human laminin): >1:11,000.
Immunofluorescence - tissue staining pattern is most consistent with that observed for laminin alpha5 in the mouse(Miner et al., 1997)
Affinity chromatography
Immunoprecipitation
Does not work for Western blotting
Optimal working dilutions must be determined by end user.
Immunofluorescence - tissue staining pattern is most consistent with that observed for laminin alpha5 in the mouse(Miner et al., 1997)
Affinity chromatography
Immunoprecipitation
Does not work for Western blotting
Optimal working dilutions must be determined by end user.
물리적 형태
UnPurified mouse ascites containing no preservatives.
분석 메모
Control
Developing striated muscle tissue
Developing striated muscle tissue
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Dysferlin associates with the developing T-tubule system in rodent and human skeletal muscle.
Klinge L, Harris J, Sewry C, Charlton R, Anderson L, Laval S, Chiu YH, Hornsey M et al.
Muscle and Nerve null
Titin mutation segregates with hereditary myopathy with early respiratory failure.
Gerald Pfeffer,Hannah R Elliott,Helen Griffin,Rita Barresi,James Miller,Julie Marsh et al.
Brain null
Congenital muscular dystrophy with primary partial laminin alpha2 chain deficiency: molecular study.
Y He et al.
Neurology, 57(7), 1319-1322 (2001-10-10)
The authors report a case of congenital muscular dystrophy with mild nonprogressive muscle weakness, white matter hypodensity, and absence of the laminin alpha2 chain in muscle fibers with two antibodies, but not with four others. They identified mutations in LAMA2
Jamie L Maciaszek et al.
Biophysical journal, 102(5), 1137-1143 (2012-03-13)
Collapse and sudden death in physical training are the most serious complications of sickle cell trait (SCT). There is evidence that erythrocytes in SCT patients aggregate during strenuous exercise, likely because of adhesive interactions with the extracellular matrix (ECM) and
S Matsubara et al.
Neuromuscular disorders : NMD, 9(6-7), 388-398 (1999-11-02)
Despite the recent advance in genetic study of Fukuyama-type congenital muscular dystrophy (FCMD), the mechanism of muscle degeneration in the disease remains unclear. To clarify it, muscle biopsies from six cases of FCMD were subjected to immunohistochemical and ultrastructural studies.
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