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Merck
모든 사진(5)

주요 문서

HCCBP3MAG-58K

Millipore

MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay

Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

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About This Item

UNSPSC 코드:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Quality Level

종 반응성

human

제조업체/상표

Milliplex®

assay range

accuracy: 74-126%
standard curve range: 0.004-3 ng/mL
(Galectin-3)

standard curve range: 0.02-20 ng/mL
(Myeloperoxidase)

standard curve range: 0.03-25 nM
(Sex Hormone Binding Globulin)

standard curve range: 0.03-25 ng/mL
(Ferritin)

standard curve range: 0.07-50 ng/mL
(Catalase, Fibroblast Activation Protein α)

standard curve range: 0.1-75 ng/mL
(Melanoma Inhibitory Activity Protein)

standard curve range: 0.27-200 ng/mL
(Cathepsin D, IGFBP3)

기술

multiplexing: suitable

검출 방법

fluorometric (Luminex xMAP)

배송 상태

wet ice

일반 설명

Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

MILLIPLEX® Human Circulating Biomarker Panel 3 is an 8-plex kit to be used for the simultaneous quantification or any or all of the following analytes in serum, plasma and tissue/cell lysate and culture supernatant samples: Galectin-3, Cathepsin D, Fibroblast activation protein alpha (FAP), Melanoma inhibitory activity protein (MIA), Myeloperoxidase, Sex hormone binding globulin (SHBG), Insulin like growth factor binding protein 3 (IGFBP3), and Ferritin. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

특이성

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

애플리케이션

  • Analytes: Cathepsin D, Ferritin, Fibroblast Activation Protein (FAP), Galectin-3, IGFBP3, Melanoma Inhibitory Activty Protein (MIA), Myeloperoxidase (MPO), Sex Hormone Binding Globulin (SHGB)
  • Recommended Sample Type: Human serum, plasma or tissue/cell culture supernatants or lysates e
  • Recommended Sample Dilution: 25 μL of 1:50 diluted plasma or serum, or 25 μL of diluted tissue/cell lysate or culture supernatant per well (dilution factors may vary). Note: If IGFBP3 is included in the assay, then the recommended dilution for the assay is 1:200
  • Assay Run Time: Overnight (16-18 hr) at 2-4°C
  • Research Category: Cancer

특징 및 장점

Design your multiplex kit by choosing available analytes within this panel.

포장

Everything you need in a single kit.

저장 및 안정성

Recommended storage for kit components is 2 - 8°C.

분석 메모

SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard

기타 정보

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

법적 정보

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

픽토그램

Skull and crossbonesEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


시험 성적서(COA)

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문서 라이브러리 방문

Juan Pablo Hinestrosa et al.
Communications medicine, 2, 29-29 (2022-05-24)
Detecting cancer at early stages significantly increases patient survival rates. Because lethal solid tumors often produce few symptoms before progressing to advanced, metastatic disease, diagnosis frequently occurs when surgical resection is no longer curative. One promising approach to detect early-stage

관련 콘텐츠

Detection of cancer biomarkers through multiplex cancer assays can accelerate studies of normal homeostasis and tumorigenic processes. See how MILLIPLEX® multiplex cancer assays are advancing various cancer research areas including lung cancer, breast cancer, and immuno-oncology research.

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