GF313

TGF- α Protein, Human Recombinant Animal Free

>98% (SDS-PAGE and HPLC), <0.1 μg/mg protein endotoxin (<1EU/μg)

• 동의어(들): Transforming growth factor alpha, TGFa, TGF alpha, EGF-like TGF, TGF type 1
• UNSPSC 코드: 12352202
• eCl@ss: 32160405
• NACRES: NA.75

속성

• 재조합: expressed in E. coli
• Quality Level: 100
• 분석: >98% (SDS-PAGE and HPLC)
• 불순물: <0.1 μg/mg protein endotoxin (<1EU/μg)
• NCBI 수납 번호: NM_001099691.1; NM_003236.2
• UniProt 수납 번호: P01135
• 배송 상태: dry ice

설명

일반 설명

Product Source: E. coli

Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.

특이성

Cross Reactivty
Chicken, Mouse, Rat

애플리케이션

Research Category
Stem Cell Research

Research Sub Category
Growth Factors & Receptors

품질

Bioactivity assay: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.

물리적 형태

Product is filtered through a 0.2 micron filter before lyophilization.

Recombinant animal free human TGF- α is manufactured using all non-animal reagents

저장 및 안정성

Store at -20°C for up to 6 months from date of receipt.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable