추천 제품
일반 설명
TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin-like loops separated by three epidermal growth factor-like repeats that are connected to three fibronectin type III-like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.
특이성
Antibody recognizes Human Tie2/TEK.
면역원
Fusion protein corresponding to residues 1-745 of human Tie2/TEK with a C-terminal His6-tag purified from infected SF-9 cells.
애플리케이션
Milli-Mark Anti-Tie2/TEK-PE Antibody, clone Ab33 is an antibody against Tie2/TEK for use in FC.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
품질
Evaluated by flow cytometry using HUVEC cells.
표적 설명
126 kDa Calculated
물리적 형태
Protein G Purified
Purified mouse monoclonal IgG1k conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.
저장 및 안정성
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
분석 메모
Control
HUVEC cells
HUVEC cells
법적 정보
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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